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Net Loss Per Share (Tables)

9 Months Ended

Sep. 30, 2018

Earnings Per Share [Abstract]

Schedule of Diluted Earnings Per Share

The following tables reconcile the components of the numerator and denominator included in the calculations of diluted net loss per share:

	Three Months Ended September 30,
	2018				2017
Numerator
Net loss (numerator for use in basic net loss per share)	$	(25,015,672	)		$	(34,134,570	)
Adjustment for decrease in fair value of warrant liability	—				(423,296		)
Numerator for use in diluted net loss per share	$	(25,015,672	)		$	(34,557,866	)
Denominator
Weighted average number of common shares outstanding (denominator for use in basic net loss per share)	92,423,122				86,952,024
Effect of dilutive potential common shares	—				138,659
Denominator for use in diluted net loss per share	92,423,122				87,090,683
Net loss per share, diluted	$	(0.27	)		$	(0.40	)
Net loss per share, basic	$	(0.27	)		$	(0.39	)

	Nine Months Ended September 30,
	2018				2017
Numerator
Net loss (numerator for use in basic net loss per share)	$	(64,005,625	)		$	(66,699,593	)
Adjustment for decrease in fair value of warrant liability	—				(227,273		)
Numerator for use in diluted net loss per share	$	(64,005,625	)		$	(66,926,866	)
Denominator
Weighted average number of common shares outstanding (denominator for use in basic net loss per share)	91,350,117				78,894,881
Effect of dilutive potential common shares	—				148,599
Denominator for use in diluted net loss per share	91,350,117				79,043,480
Net loss per share, diluted	$	(0.70	)		$	(0.85	)
Net loss per share, basic	$	(0.70	)		$	(0.85	)

Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share

The following table summarizes potential shares of common stock that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect for the three and nine months ended September 30, 2018 and 2017:

Common Stock Equivalents	2018			2017
Options to purchase common stock	8,945,275			7,811,387
Restricted stock units	1,711,213			1,324,410
Convertible preferred stock	8,456			8,456
Total	10,664,944			9,144,253

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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Tabular disclosure of the effect of income (loss) on an entity's diluted earnings per share.

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