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Summary of Significant Accounting Policies - Antidilutive Securities Table (Details) - shares	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total antidilutive securities (shares)	10,449,150	8,937,494	7,897,564
Options to purchase common stock
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total antidilutive securities (shares)	8,752,677	7,694,870	6,806,183
Warrants to purchase common stock
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total antidilutive securities (shares)	0	0	284,091
Restricted stock units
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total antidilutive securities (shares)	1,688,017	1,234,168	798,834
Convertible preferred stock
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect
Total antidilutive securities (shares)	8,456	8,456	8,456

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- Definition

Common stock equivalents.

+ References

No definition available.

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- Definition

Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257

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