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Major Customers and Concentration of Credit Risk (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Concentration Risk [Line Items]                      
Total revenues $ 2,502,624 $ 2,000,868 $ 24,448,761 $ 1,529,644 $ 8,787,234 $ 2,644,543 $ 20,412,124 $ 10,376,185 $ 30,481,897 $ 42,220,086 $ 35,368,361
Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 100.00% 100.00% 100.00%
ApolloBio                      
Concentration Risk [Line Items]                      
Total revenues                 $ 23,000,000 $ 0 $ 0
ApolloBio | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 75.00% 0.00% 0.00%
AstraZeneca                      
Concentration Risk [Line Items]                      
Total revenues                 $ 6,850,424 $ 22,269,773 $ 1,518,639
Accounts receivable $ 3,200,000               $ 3,200,000   $ 1,700,000
AstraZeneca | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 23.00% 53.00% 4.00%
AstraZeneca | Accounts Receivable | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 98.00%   28.00%
DARPA                      
Concentration Risk [Line Items]                      
Total revenues                 $ 0 $ 9,983,927 $ 26,602,183
Accounts receivable         $ 4,100,000         $ 4,100,000  
DARPA | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 0.00% 24.00% 75.00%
DARPA | Accounts Receivable | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                   69.00%  
Roche                      
Concentration Risk [Line Items]                      
Total revenues                 $ 0 $ 6,107,254 $ 4,917,929
Roche | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 0.00% 14.00% 14.00%
GeneOne (affiliated entity)                      
Concentration Risk [Line Items]                      
Total revenues                 $ 342,386 $ 551,208 $ 1,188,432
GeneOne (affiliated entity) | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 1.00% 1.00% 4.00%
All other                      
Concentration Risk [Line Items]                      
Total revenues                 $ 289,087 $ 3,307,924 $ 1,141,178
All other | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 1.00% 8.00% 3.00%