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Stockholders' Equity - Summary of Stock Option Activity Under Equity Incentive Plan (Details)
12 Months Ended
Dec. 31, 2018
$ / shares
shares
Number of Shares  
Beginning Balance (shares) | shares 7,694,870
Granted (shares) | shares 2,176,935
Exercised (shares) | shares (472,762)
Cancelled (shares) | shares (646,366)
Ending Balance (shares) | shares 8,752,677
Weighted-Average Exercise Price  
Beginning Balance ($ per share) | $ / shares $ 6.77
Granted ($ per share) | $ / shares 4.32
Exercised ($ per share) | $ / shares 3.21
Cancelled ($ per share) | $ / shares 6.83
Ending Balance ($ per share) | $ / shares $ 6.35