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Related Party Transactions (Details) - USD ($)	1 Months Ended					12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Mar. 31, 2016	Jan. 31, 2016	May 31, 2015	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2013	Dec. 31, 2010
Related Party Transaction [Line Items]
Full payment						$ 0	$ 1,000,000	$ 1,000,000
Long-term other assets	$ 2,639,354					2,669,998	2,639,354
Grant proceeds received						9,500,000
Plumbline Life Sciences
Related Party Transaction [Line Items]
Revenue from related parties						107,000	215,000
Accounts receivable	370,000					$ 478,000	370,000
Available-for-sale Securities
Related Party Transaction [Line Items]
Number of shares owned (shares)						395,758
GeneOne (affiliated entity)
Related Party Transaction [Line Items]
Payment received for license granted										$ 3,000,000
Term									20 years
Ownership target				35.00%	35.00%
Full payment	1,000,000
Revenue from related parties						$ 342,000	551,000	1,200,000
Operating expenses related to affiliated entity						7,000,000	2,300,000	$ 2,800,000
Accounts payable/accrued liability	107,000					372,000	107,000
Long-term other assets	331,000					$ 381,000	331,000
Number of shares owned (shares)						1,644,155
Director
Related Party Transaction [Line Items]
Term			5 years
Revenue from related parties							2,600,000
Operating expenses related to affiliated entity						$ 1,800,000	2,300,000
Accounts receivable	117,000					258,000	117,000
Expenses to reimburse			$ 3,100,000
Proceeds from sub-grant		$ 6,100,000
Grant proceeds received						3,300,000
Due to related parties	$ 820,000					$ 554,000	$ 820,000

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