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The amount of total capital as defined in the regulations.

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Cash includes currency on hand as well as demand deposits with banks or financial institutions. It also includes other kinds of accounts that have the general characteristics of demand deposits in that the customer may deposit additional funds at any time and effectively may withdraw funds at any time without prior notice or penalty. Cash equivalents, excluding items classified as marketable securities, include short-term, highly liquid Investments that are both readily convertible to known amounts of cash, and so near their maturity that they present minimal risk of changes in value because of changes in interest rates. Generally, only investments with original maturities of three months or less qualify under that definition. Original maturity means original maturity to the entity holding the investment. For example, both a three-month US Treasury bill and a three-year Treasury note purchased three months from maturity qualify as cash equivalents. However, a Treasury note purchased three years ago does not become a cash equivalent when its remaining maturity is three months. Short-term investments, exclusive of cash equivalents, generally consist of marketable securities intended to be sold within one year (or the normal operating cycle if longer) and may include trading securities, available-for-sale securities, or held-to-maturity securities (if maturing within one year), as applicable.

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Face (par) amount of debt instrument at time of issuance.

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Contractual interest rate for funds borrowed, under the debt agreement.

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The total amount of investments that are intended to be held for an extended period of time (longer than one operating cycle).

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The equity interest of noncontrolling shareholders, partners or other equity holders in consolidated entity.

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No definition available.

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The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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The cash inflow from the additional capital contribution to the entity.

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The cash inflow during the period from additional borrowings in aggregate debt. Includes proceeds from short-term and long-term debt.

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The cumulative amount of the reporting entity's undistributed earnings or deficit.

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Basis of Presentation (Details) - USD ($)		3 Months Ended		12 Months Ended
Basis of Presentation (Details) - USD ($)	Mar. 01, 2019	Mar. 31, 2019	Mar. 31, 2018	Dec. 31, 2018
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Net loss		$ 29,219,262	$ 32,350,828
Working capital		107,500,000
Retained earnings (accumulated deficit)		(649,645,698)		$ (620,426,436)
Cash, cash equivalents, and short-term investments		128,000,000
Long-term investments		8,700,000
Proceeds from issuance of stock		$ 907,330	$ 0
Geneos Therapeutics, Inc.
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Non-controlling interest		39.00%
VGX Animal Health, Inc
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Non-controlling interest		15.00%
Common Stock \| Sales Agreement
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Stock sales agreement, remaining authorized sales amount		$ 71,100,000
Proceeds from issuance of stock		907,000		$ 29,200,000
6.50% Convertible Senior Notes Due 2024 \| Convertible Debt
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Proceeds from issuance of debt	$ 75,700,000	75,700,000
Principal amount	$ 78,500,000.0	$ 78,500,000
Debt instrument, interest rate, stated percentage		6.50%