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Condensed Consolidated Statements of Stockholders' Equity Statement - USD ($)
Total
Preferred Stock
Common Stock
Additional Paid-in Capital
Retained Earnings
AOCI Attributable to Parent
Noncontrolling Interest
Beginning balance (shares) at Dec. 31, 2017   23 90,357,644        
Beginning balance at Dec. 31, 2017 $ 142,488,809 $ 0 $ 90,358 $ 665,775,504 $ (523,356,317) $ (117,005) $ 96,269
Exercise of stock options for cash and vesting of RSUs, net of tax payments (shares)     347,287        
Exercise of stock options for cash and vesting of RSUs, net of tax payments (506,403)   $ 347 (506,750)      
Stock-based compensation 3,575,750     3,575,750      
Net loss attributable to common stockholders (32,350,828)       (32,350,828)    
Unrealized gain on short-term investments, net of tax (112,765)         (112,765)  
Ending balance (shares) at Mar. 31, 2018   23 90,704,931        
Ending balance at Mar. 31, 2018 113,094,563 $ 0 $ 90,705 668,844,504 (555,475,779) (461,136) 96,269
Beginning balance (shares) at Dec. 31, 2018   23 97,225,810        
Beginning balance at Dec. 31, 2018 87,032,407 $ 0 $ 97,226 707,794,215 (620,426,436) (528,867) 96,269
Issuance of common stock for cash (shares)     183,200        
Issuance of common stock for cash 907,330   $ 183 907,147      
Exercise of stock options for cash and vesting of RSUs, net of tax payments (shares)     525,000        
Exercise of stock options for cash and vesting of RSUs, net of tax payments (719,397)   $ 525 (719,922)      
Equity component of issuance of convertible notes 15,752,698     15,752,698      
Stock-based compensation 3,432,796     3,432,796      
Acquisition of non-controlling interest in Geneos 3,030,107           3,030,107
Net loss attributable to common stockholders (29,288,867)       (29,219,262)   (69,605)
Unrealized gain on short-term investments, net of tax 819,177         819,177  
Ending balance (shares) at Mar. 31, 2019   23 97,934,010        
Ending balance at Mar. 31, 2019 $ 80,966,251 $ 0 $ 97,934 $ 727,166,934 $ (649,645,698) $ 290,310 $ 3,056,771