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v3.19.3

Basis of Presentation (Details) |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | --- | --- | ---
Aug. 01, 2019 USD ($) | Mar. 01, 2019 USD ($) | Jul. 31, 2019 | Sep. 30, 2019 USD ($) | Sep. 30, 2018 USD ($) | Sep. 30, 2019 USD ($) | Sep. 30, 2018 USD ($) | Dec. 31, 2018 USD ($) | Aug. 01, 2019 KRW (₩)
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |
Net loss |  |  |  | $ 23,090,693 | $ 25,015,672 | $ 81,697,181 | $ 64,005,625 |  |
Working capital |  |  |  | 79,300,000 |  | 79,300,000 |  |  |
Retained earnings (accumulated deficit) |  |  |  | (702,123,617) |  | (702,123,617) |  | $ (620,426,436) |
Cash, cash equivalents, and short-term investments |  |  |  | 93,800,000 |  | 93,800,000 |  |  |
Long-term investments |  |  |  | 8,000,000 |  | 8,000,000 |  |  |
Proceeds from issuance of stock |  |  |  |  |  | $ 3,425,065 | $ 14,923,263 |  |
Expected number of positions to be eliminated, percent |  |  | 28.00% |  |  |  |  |  |
Restructuring charges |  |  |  | $ 2,200,000 |  |  |  |  |
Geneos Therapeutics, Inc. |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |
Non-controlling interest |  |  |  | 39.00% |  | 39.00% |  |  |
VGX Animal Health, Inc |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |
Non-controlling interest |  |  |  | 15.00% |  | 15.00% |  |  |
Common stock | Sales Agreement |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |
Stock sales agreement, remaining authorized sales amount |  |  |  | $ 68,500,000 |  | $ 68,500,000 |  |  |
Proceeds from issuance of stock |  |  |  | 1,100,000 |  | 3,400,000 |  | $ 29,200,000 |
6.50% Convertible Senior Notes Due 2024 | Convertible Debt |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |
Proceeds from issuance of debt |  | $ 75,700,000 |  |  |  | 75,700,000 |  |  |
Principal amount |  | $ 78,500,000.0 |  | $ 78,500,000 |  | $ 78,500,000 |  |  |
Debt instrument, interest rate, stated percentage |  | 6.50% |  | 6.50% |  | 6.50% |  |  |
Korean Won Convertible Bonds Due 2024 | Convertible Debt |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |
Proceeds from issuance of debt | $ 14,500,000 |  |  |  |  |  |  |  |
Principal amount | $ 15,000,000 |  |  | $ 15,052,055 |  | $ 15,052,055 |  |  | ₩ 18,000,000,000
Debt instrument, interest rate, stated percentage | 1.00% |  |  |  |  |  |  |  | 1.00%

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