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Income Taxes Significant Components of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Deferred tax assets: |  |
Capitalized research expense | $ 6,300 | $ 7,408
NOL carryforwards | 110,788 | 89,399
Research and development and other tax credits | 11,737 | 9,432
Deferred revenue | 1,506 | 985
Deferred rent | 0 | 2,013
Stock-based compensation | 3,255 | 3,408
Acquired intangibles | 889 | 912
Derivative liability | 1,852 | 0
Interest expense | 1,122 | 0
Investment in affiliated entity | 645 | 0
Lease liability | 4,722 | 0
Other | 2,413 | 2,693
Deferred tax assets, gross | 145,229 | 116,250
Valuation allowance | (137,159) | (115,007)
Total deferred tax assets | 8,070 | 1,243
Deferred tax liabilities: |  |
Acquired intangibles | (160) | (142)
Investment in affiliated entity | 0 | (4)
Right of use asset | (2,894) | 0
Note discount | (2,862) | 0
Convertible note | (1,381) | 0
Fixed assets | (805) | (1,121)
Net deferred tax liabilities | $ (32) | $ (24)

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