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Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2019
Accounting Policies [Abstract] |
Schedule of Earnings Per Share, Basic and Diluted | The following tables reconcile the components of the numerator and denominator included in the calculations of diluted net loss per share:
| Year Ended December 31,
| 2019 |  | 2018 |  | 2017
Numerator |  |  |  |  |
Net loss attributable to Inovio Pharmaceuticals, Inc. (numerator for use in basic net loss per share) | $ | (119,359,219 | ) |  | $ | (96,967,830 | ) |  | $ | (88,205,772 | )
Adjustment for decrease in fair value of warrant liability | — |  |  | — |  |  | (806,819 | )
Numerator for use in diluted net loss per share | $ | (119,359,219 | ) |  | $ | (96,967,830 | ) |  | $ | (89,012,591 | )
Denominator |  |  |  |  |
Weighted average number of common shares outstanding (denominator for use in basic net loss per share) | 98,717,999 |  |  | 92,539,997 |  |  | 81,777,493 |
Effect of dilutive potential common shares | — |  |  | — |  |  | 140,529 |
Denominator for use in diluted net loss per share | 98,717,999 |  |  | 92,539,997 |  |  | 81,918,022 |
Net loss per share, diluted | $ | (1.21 | ) |  | $ | (1.05 | ) |  | $ | (1.09 | )
Net loss per share, basic | $ | (1.21 | ) |  | $ | (1.05 | ) |  | $ | (1.08 | )
Summary of common shares that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect | The following table summarizes potential shares of common stock that were excluded from diluted net loss per share calculation because of their anti-dilutive effect:
| Year Ended December 31,
| 2019 |  | 2018 |  | 2017
Options to purchase common stock | 9,265,390 |  |  | 8,752,677 |  |  | 7,694,870 |
Restricted stock units | 2,069,936 |  |  | 1,688,017 |  |  | 1,234,168 |
Convertible preferred stock | 8,456 |  |  | 8,456 |  |  | 8,456 |
Convertible notes | 14,585,653 |  |  | — |  |  | — |
August 2019 Bonds | 3,799,071 |  |  | — |  |  | — |
December 2019 Bonds | 1,009,450 |  |  | — |  |  | — |
Total | 30,737,956 |  |  | 10,449,150 |  |  | 8,937,494 |
Summary of assumptions used to estimate the fair value of stock options | The weighted average assumptions used in the Black-Scholes model for option grants to employees and directors are presented below:
| Year Ended December 31,
| 2019 |  | 2018 |  | 2017
Risk-free interest rate | 2.42% |  | 2.73% |  | 2.20%
Expected volatility | 70% |  | 72% |  | 73%
Expected life in years | 6 |  | 6 |  | 6
Dividend yield | — |  | — |  | —
The weighted average assumptions used in the Black-Scholes model for option grants to non-employees are presented below:
| Year Ended December 31,
| 2019 |  | 2018 |  | 2017
Risk-free interest rate | 2.45% |  | 2.71% |  | 2.42%
Expected volatility | 88% |  | 78% |  | 99%
Expected life in years | 10 |  | 9 |  | 9
Dividend yield | — |  | — |  | —
Schedule of New Accounting Pronouncements and Changes in Accounting Principles | The impact of the adoption of Topic 842 on the consolidated balance sheets as of January 1, 2019 was as follows:
| ASC 840 |  |  |  | Topic 842
| January 1, 2019 |  | Impact of Adoption |  | January 1, 2019
Deferred rent, current portion | $ | 1,065,387 |  |  | $ | (1,065,387 | ) |  | $ | — |
Deferred rent, non-current portion | $ | 8,518,207 |  |  | $ | (8,518,207 | ) |  | $ | — |
Operating right-of-use assets | $ | — |  |  | $ | 14,634,769 |  |  | $ | 14,634,769 |
Operating lease liability, current portion | $ | — |  |  | $ | 1,733,600 |  |  | $ | 1,733,600 |
Operating lease liability, non-current portion | $ | — |  |  | $ | 22,484,763 |  |  | $ | 22,484,763 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=116856206&loc=d3e5070-113901 + Details
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