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Consolidated Statements of Operations - USD ($)
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Revenues:      
Total revenues $ 4,111,930 $ 30,481,897 $ 42,220,086
Operating expenses:      
Research and development 88,017,319 95,257,876 98,572,618
General and administrative 27,203,156 29,315,159 28,290,369
Gain on sale of assets 0 0 (1,000,000)
Total operating expenses 115,220,475 124,573,035 125,862,987
Loss from operations (111,108,545) (94,091,138) (83,642,901)
Other income (expense):      
Interest income 2,605,981 2,264,747 1,836,451
Interest expense (7,948,539) 0 (25,933)
Change in fair value of common stock warrants 0 360,795 806,819
Change in fair value of derivative liability (1,763,652) 0 0
Loss on investment in affiliated entities (3,090,557) (1,988,567) (6,982,664)
Other income (expense), net 496,200 (1,343,856) (197,544)
Net loss before income tax benefit/(provision for income tax) (120,809,112) (94,798,019) (88,205,772)
Income tax benefit (provision for income taxes) 257,335 (2,169,811) 0
Net loss (120,551,777) (96,967,830) (88,205,772)
Net loss attributable to non-controlling interest 1,192,558 0 0
Net loss attributable to Inovio Pharmaceuticals, Inc. $ (119,359,219) $ (96,967,830) $ (88,205,772)
Net loss per share attributable to Inovio Pharmaceuticals, Inc. stockholders      
Basic ($ per share) $ (1.21) $ (1.05) $ (1.08)
Diluted ($ per share) $ (1.21) $ (1.05) $ (1.09)
Weighted average number of common shares outstanding      
Basic (shares) 98,717,999 92,539,997 81,777,493
Diluted (shares) 98,717,999 92,539,997 81,918,022
Revenue under collaborative research and development arrangements      
Revenues:      
Total revenues $ 3,636,945 $ 29,860,785 $ 28,407,388
Revenue under collaborative research and development arrangements with affiliated entities      
Revenues:      
Total revenues 235,649 449,524 765,828
Miscellaneous revenue, including from affiliated entities      
Revenues:      
Total revenues 237,536 171,588 10,474,539
Grants and miscellaneous revenue from affiliated entity      
Revenues:      
Total revenues $ 1,800 $ 0 $ 2,572,331