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Major Customers and Concentration of Credit Risk (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Concentration Risk [Line Items]                      
Total revenues $ 279,488 $ 866,863 $ 135,673 $ 2,829,905 $ 2,502,624 $ 2,000,868 $ 24,448,761 $ 1,529,644 $ 4,111,930 $ 30,481,897 $ 42,220,086
Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 100.00% 100.00% 100.00%
ApolloBio                      
Concentration Risk [Line Items]                      
Total revenues                 $ 0 $ 23,000,000 $ 0
ApolloBio | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 0.00% 75.00% 0.00%
AstraZeneca                      
Concentration Risk [Line Items]                      
Total revenues                 $ 3,194,877 $ 6,850,424 $ 22,269,773
Accounts receivable 161,000       $ 3,200,000       $ 161,000 $ 3,200,000  
AstraZeneca | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 78.00% 23.00% 53.00%
AstraZeneca | Accounts Receivable | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 23.00% 98.00%  
DARPA                      
Concentration Risk [Line Items]                      
Total revenues                 $ 0 $ 0 $ 9,983,927
DARPA | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 0.00% 0.00% 24.00%
Roche                      
Concentration Risk [Line Items]                      
Total revenues                 $ 0 $ 0 $ 6,107,254
Roche | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 0.00% 0.00% 14.00%
All other, including affiliated entities                      
Concentration Risk [Line Items]                      
Total revenues                 $ 917,053 $ 631,473 $ 3,859,132
All other, including affiliated entities | Revenue | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 22.00% 2.00% 9.00%
MCDC                      
Concentration Risk [Line Items]                      
Accounts receivable $ 469,000               $ 469,000    
MCDC | Accounts Receivable | Customer Concentration Risk                      
Concentration Risk [Line Items]                      
Concentration risk, percentage                 67.00%