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Related Party Transactions (Details) - USD ($)
 1 Months Ended 12 Months Ended
Dec. 31, 2017
Nov. 30, 2016
Mar. 31, 2016
Jan. 31, 2016
May 31, 2015
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2013
Dec. 31, 2010
Related Party Transaction [Line Items]                    
Full payment           $ 0 $ 0 $ 1,000,000    
Long-term other assets           $ 2,672,024 2,669,998      
GeneOne (affiliated entity)                    
Related Party Transaction [Line Items]                    
Number of shares owned (shares)           1,644,155        
Payment received for license granted                   $ 3,000,000
Term                 20 years  
Ownership target       35.00% 35.00%          
Full payment $ 1,000,000                  
Revenue from related parties           $ 127,000 342,000 551,000    
Operating expenses related to affiliated entity           2,500,000 7,000,000 $ 2,300,000    
Accounts payable/accrued liability           511,000 372,000      
Long-term other assets           284,000 381,000      
Accounts receivable           $ 128,000 0      
PLS (affiliated entity)                    
Related Party Transaction [Line Items]                    
Number of shares owned (shares)           395,758        
Revenue from related parties           $ 111,000 107,000      
Accounts receivable           589,000 478,000      
The Wistar Institute                    
Related Party Transaction [Line Items]                    
Term     5 years              
Operating expenses related to affiliated entity           1,500,000 1,800,000      
Accounts receivable           616,000 258,000      
Expenses to reimburse     $ 3,100,000              
Proceeds from sub-grant   $ 6,100,000                
Grant proceeds received           2,200,000 3,300,000      
Due to related parties           219,000 $ 554,000      
Deferred grant funding from affiliate           $ 843,000