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Stock-Based Compensation (Details) - USD ($)
3 Months Ended 9 Months Ended
Aug. 28, 2020
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation       $ 11,822,483 $ 8,867,810
Total unrecognized compensation cost related to unvested stock options   $ 9,700,000   $ 9,700,000  
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years)       2 years 2 months 12 days  
Weighted average grant date fair value (in dollars per share)   $ 12.09 $ 1.65 $ 6.78 $ 2.20
Performance-based restricted stock units          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Total unrecognized compensation cost related to unvested stock options   $ 13,000,000.0   $ 13,000,000.0  
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years)       2 years 1 month 6 days  
Weighted average grant date fair value, restricted stock units (in dollars per share)     $ 2.68 $ 9.12 $ 3.09
Granted (in shares)   0      
Research and Development Expense          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Allocated share-based compensation expense   $ 2,100,000 $ 922,000 $ 6,200,000 $ 5,100,000
General and Administrative Expense          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Allocated share-based compensation expense   1,800,000 885,000 $ 4,800,000 3,000,000.0
2016 Incentive Plan          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Award vesting period (in years)       3 years  
2016 Incentive Plan | Performance-based restricted stock units          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Weighted average grant date fair value, restricted stock units (in dollars per share) $ 12.06        
Granted (in shares) 663,353        
Grant date fair value $ 8,000,000.0        
2016 Incentive Plan | Performance-based restricted stock units | Tranche One          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting percentage 50.00%        
2016 Incentive Plan | Performance-based restricted stock units | Tranche Two          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting percentage 50.00%        
Award vesting period (in years) 1 year        
Employees and Directors          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation   $ 3,900,000 $ 1,800,000 $ 11,000,000.0 $ 8,100,000
Employees and Directors | Stock Options          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Risk-free interest rate   0.35% 1.75% 0.64% 2.43%
Expected volatility   85.00% 65.00% 77.00% 70.00%
Expected life in years   5 years 10 months 24 days 6 years 1 month 6 days 5 years 10 months 24 days 6 years 2 months 12 days
Dividend yield   0.00% 0.00% 0.00% 0.00%
Non Employee          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation   $ 278,000 $ 264,000 $ 884,000 $ 744,000