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Income Taxes Significant Components of Deferred Tax Assets and Liabilities (Details) - USD ($) $ in Thousands | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | ---
Deferred tax assets: |  |
Capitalized research expense | $ 5,250 | $ 6,300
NOL carryforwards | 127,835 | 110,788
Research and development and other tax credits | 13,242 | 11,737
Deferred revenue | 1,628 | 1,506
Stock-based compensation | 3,256 | 3,255
Acquired intangibles | 757 | 889
Derivative liability | 0 | 1,852
Interest expense | 564 | 1,122
Investment in affiliated entity | 542 | 645
Lease liability | 4,283 | 4,722
Other | 6,127 | 2,413
Deferred tax assets, gross | 163,484 | 145,229
Valuation allowance | (159,705) | (137,159)
Total deferred tax assets | 3,779 | 8,070
Deferred tax liabilities: |  |
Acquired intangibles | (179) | (160)
Right of use asset | (2,676) | (2,894)
Note discount | (469) | (2,862)
Convertible note | 0 | (1,381)
Fixed assets | (487) | (805)
Net deferred tax liabilities | $ (32) | $ (32)

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