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Related Party Transactions
12 Months Ended
Dec. 31, 2020
Related Party Transaction, Due from (to) Related Party [Abstract]  
Related Party Transactions Related Party Transactions
GeneOne Life Sciences
On August 27, 2020, the Company sold 1,644,155 shares of common stock in GeneOne for net proceeds of approximately 47.4 billion KRW (approximately USD $40.1 million based on the exchange rate on the date of sale). The Company no longer holds an investment in GeneOne shares and GeneOne is no longer considered a related party to the Company under ASC 850. The Company's consolidated balance sheet as of December 31, 2020 no longer reflects GeneOne’s portion in accounts receivable and accounts payable and accrued expenses with affiliated entities, whereas the Company’s balance sheet as of December 31, 2019 reflects $128,000 and $511,000 in accounts receivable and accounts payable and accrued expenses with
affiliated entities, respectively, related to GeneOne. Revenues recognized from GeneOne will no longer be presented as revenue with affiliated entity on the consolidated statement of operations after the change in related party designation in August 2020.
Revenue recognized from GeneOne for the years ended December 31, 2020, 2019 and 2018 consisting of patent, device maintenance and licensing fees was $125,000, $127,000 and $342,000, respectively.
Operating expenses recorded from transactions with GeneOne related primarily to biologics manufacturing and were $4.7 million, $2.5 million and $7.0 million for the years ended December 31, 2020, 2019 and 2018, respectively.
Plumbline Life Sciences, Inc.
The Company owned 597,808 shares of common stock in Plumbline Life Sciences, Inc. ("PLS") as of December 31, 2020 and one of the Company's directors, Dr. David B. Weiner, acts as a consultant to PLS.
On February 20, 2020, the Company entered into a Debt and Share Subscription Agreement with PLS under which the Company received 202,050 shares of PLS common stock in exchange for a portion of the outstanding accounts receivable balance due from PLS. Following the issuance of these shares and as of December 31, 2020, the Company held a 19.7% ownership interest in PLS.
Revenue recognized from PLS consists of milestone, license and patent fees. For the years ended December 31, 2020 and 2019, the Company recognized revenue from PLS of $1.4 million and $111,000, respectively. At December 31, 2020 and 2019, the Company had an accounts receivable balance of $67,000 and $589,000, respectively, related to PLS.

The Wistar Institute
The Company's director Dr. David B. Weiner is a director of the Vaccine Center of The Wistar Institute ("Wistar"). Dr. Weiner is also the Executive Vice President of Wistar.
In March 2016, the Company entered into collaborative research agreements with Wistar for preventive and therapeutic DNA-based immunotherapy applications and products developed by Dr. Weiner and Wistar for the treatment of cancers and infectious diseases. Under the terms of the agreement, the Company will reimburse Wistar for all direct and indirect costs incurred in the conduct of the collaborative research, not to exceed $3.1 million during the five-year term of the agreement. The Company will have the exclusive right to in-license new intellectual property developed in this agreement.
In November 2016, the Company received a $6.1 million sub-grant through Wistar to develop a DMAb against the Zika infection, with funding through December 2020.
The Company is also a collaborator with Wistar on an Integrated Preclinical/Clinical AIDS Vaccine Development grant from the NIAID, with funding through February 2021.
In 2020, the Company received a $10.7 million sub-grant through Wistar for the preclinical development and translational studies of DMAbs as countermeasures for COVID-19, with funding through September 2022. The sub-grant also includes an option for an additional $6.0 million in funding through September 2024.
Deferred grant funding recognized from Wistar and recorded as contra-research and development expense is related to work performed by the Company on the research sub-contract agreements. For the years ended December 31, 2020 and 2019, the Company recorded $1.9 million and $2.2 million, respectively, as contra-research and development expense from Wistar.
Research and development expenses recorded from Wistar relate primarily to the collaborative research agreements and sub-contract agreements related to Gates and CEPI (see Note 4). Research and development expenses recorded from Wistar for the years ended December 31, 2020 and 2019 were $2.3 million and $1.5 million, respectively. At December 31, 2020 and 2019, the Company had an accounts receivable balance of $425,000 and $616,000, respectively, and an accounts payable and accrued liability balance of $643,000 and $219,000, respectively, related to Wistar. As of December 31, 2020, the Company had $96,000 recorded as grant funding liability on its consolidated balance sheet related to Wistar.