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Consolidated Statements of Comprehensive Loss - USD ($)	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018
Statement of Comprehensive Income [Abstract]
Net loss	$ (167,474,914)	$ (120,551,777)	$ (96,967,830)
Other comprehensive income (loss):
Foreign currency translation	27,205	0	0
Unrealized gain (loss) on short-term investments, net of tax	(755,963)	1,001,475	(180,496)
Comprehensive loss	(168,203,672)	(119,550,302)	(97,148,326)
Comprehensive loss attributable to non-controlling interest	1,063,757	1,192,558	0
Comprehensive loss attributable to Inovio Pharmaceuticals, Inc.	$ (167,139,915)	$ (118,357,744)	$ (97,148,326)

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