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Basis of Presentation, Liquidity and Risks and Uncertainties (Details) - USD ($)	3 Months Ended		12 Months Ended
	Mar. 31, 2021	Mar. 31, 2020	Dec. 31, 2020
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Net loss	$ 54,402,131	$ 32,541,054
Working capital	546,900,000
Retained earnings (accumulated deficit)	(960,598,943)		$ (906,196,812)
Cash, cash equivalents, and short-term investments	518,600,000
Proceeds from issuance of stock	$ 162,105,030	$ 208,241,933
Common stock | Underwritten Public Offering
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Proceeds from issuance of stock			162,100,000
Common stock | Sales Agreements
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Proceeds from issuance of stock			$ 454,500,000

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