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Basis of Presentation, Liquidity and Risks and Uncertainties (Details) - USD ($)
 3 Months Ended 6 Months Ended
Jun. 30, 2021
Mar. 31, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2020
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Net loss $ 82,139,958   $ 128,703,059 $ 136,542,089 $ 161,244,113  
Working capital 490,700,000     490,700,000    
Retained earnings (accumulated deficit) 1,042,738,901     1,042,738,901   $ 906,196,812
Cash, cash equivalents, and short-term investments $ 443,700,000     443,700,000    
Proceeds from issuance of stock       $ 162,105,030 $ 329,960,855  
Common stock | Underwritten Public Offering            
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Proceeds from issuance of stock   $ 162,100,000        
Common stock | Sales Agreements            
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Proceeds from issuance of stock   $ 454,500,000