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Stock-Based Compensation (Details) - USD ($)
3 Months Ended 9 Months Ended
Aug. 28, 2020
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation       $ 20,862,757 $ 11,822,483
Total unrecognized compensation cost related to unvested stock options   $ 18,600,000   $ 18,600,000  
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years)       2 years 2 months 12 days  
Weighted average grant date fair value (in dollars per share)   $ 6.40 $ 12.09 $ 7.75 $ 6.78
2016 Incentive Plan          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Award vesting period (in years)       3 years  
Research and Development Expense          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Allocated share-based compensation expense   $ 2,800,000 $ 2,100,000 $ 10,700,000 $ 6,200,000
General and Administrative Expense          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Allocated share-based compensation expense   2,500,000 1,800,000 9,100,000 4,800,000
Employees and Directors          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation   5,300,000 3,900,000 19,800,000 11,000,000
Non Employee          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Stock-based compensation   $ 311,000 $ 278,000 $ 1,000,000 $ 884,000
Stock Options | Employees and Directors          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Risk-free interest rate   0.90% 0.35% 0.90% 0.64%
Expected volatility   94.00% 85.00% 93.00% 77.00%
Expected life in years   5 years 8 months 12 days 5 years 10 months 24 days 5 years 9 months 18 days 5 years 10 months 24 days
Dividend yield   0.00% 0.00% 0.00% 0.00%
Performance-based restricted stock units          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Total unrecognized compensation cost related to unvested stock options   $ 15,900,000   $ 15,900,000  
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years)       2 years  
Weighted average grant date fair value, restricted stock units (in dollars per share)   $ 8.63 $ 0 $ 10.37 $ 9.12
Performance-based restricted stock units | 2016 Incentive Plan          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Weighted average grant date fair value, restricted stock units (in dollars per share) $ 12.06        
Granted (in shares) 663,353        
Grant date fair value $ 8,000,000        
Performance-based restricted stock units | 2016 Incentive Plan | Tranche One          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting percentage 50.00%        
Performance-based restricted stock units | 2016 Incentive Plan | Tranche Two          
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]          
Vesting percentage 50.00%        
Award vesting period (in years) 1 year