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Goodwill and Intangible Assets | 12 Months Ended
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Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract] |
Goodwill and Intangible Assets | Goodwill and Intangible Assets The following sets forth goodwill and intangible assets by major asset class:
|  |  | December 31, 2021 |  | December 31, 2020
| Weighted Average Useful Life (Yrs) | Gross |  | Accumulated Amortization |  | Net Book Value |  | Gross |  | Accumulated Amortization |  | Net Book Value
Indefinite lived: |  |  |  |  |  |  |  |  |  |  |  |  |
Goodwill |  |  | $ | 10,513,371 |  |  | $ | — |  |  | $ | 10,513,371 |  |  | $ | 10,513,371 |  |  | $ | — |  |  | $ | 10,513,371 |
Definite lived: |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses | 10 |  | 1,323,761 |  |  | (1,305,600) |  |  | 18,161 |  |  | 1,323,761 |  |  | (1,276,852) |  |  | 46,909 |
Bioject (a) | 12 |  | 5,100,000 |  |  | (2,735,556) |  |  | 2,364,444 |  |  | 5,100,000 |  |  | (2,468,889) |  |  | 2,631,111 |
Other (b) | 18 |  | 4,050,000 |  |  | (3,806,250) |  |  | 243,750 |  |  | 4,050,000 |  |  | (3,581,250) |  |  | 468,750 |
Total intangible assets | 11 |  | 10,473,761 |  |  | (7,847,406) |  |  | 2,626,355 |  |  | 10,473,761 |  |  | (7,326,991) |  |  | 3,146,770 |
Total goodwill and intangible assets |  |  | $ | 20,987,132 |  |  | $ | (7,847,406) |  |  | $ | 13,139,726 |  |  | $ | 20,987,132 |  |  | $ | (7,326,991) |  |  | $ | 13,660,141 |
(a)Bioject intangible assets represent the estimated fair value of developed technology and intellectual property which were recorded from an asset acquisition. (b)Other intangible assets represent the estimated fair value of acquired intellectual property. Aggregate amortization expense on intangible assets was $520,000, $547,000 and $1.1 million for the years ended December 31, 2021, 2020 and 2019, respectively. Amortization expense related to intangible assets at December 31, 2021 is expected to be incurred as follows:
Year ending December 31, |
2022 | $ | 493,000 |
2023 | 276,000 |
2024 | 253,000 |
2025 | 253,000 |
2026 | 253,000 |
Thereafter | 1,098,000 |
| $ | 2,626,000 |
There were no impairment or impairment indicators present and no losses were recorded during the years ended December 31, 2021, 2020 and 2019, respectively.

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- Definition The entire disclosure for goodwill and intangible assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -URI http://asc.fasb.org/topic&trid=2144416 + Details
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