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Revenue Recognition and Concentration of Credit Risk (Tables) | 12 Months Ended
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Dec. 31, 2021
Revenue from Contract with Customer [Abstract] |
Schedule of Revenue from External Customers | The following table indicates the percentage of total revenues in excess of 10% with any single customer:
Customer | 2021 Revenue |  | % of Total Revenue |  | 2020 Revenue |  | % of Total Revenue |  | 2019 Revenue |  | % of Total Revenue
AstraZeneca | $ | 41,659 |  |  | 2 | % |  | $ | 170,587 |  |  | 2 | % |  | $ | 3,194,877 |  |  | 78 | %
Advaccine | — |  |  | — |  |  | 5,000,000 |  |  | 68 |  |  | — |  |  | — |
Plumbline Life Sciences, Inc. (affiliated entity) | 245,310 |  |  | 14 |  |  | 1,370,396 |  |  | 18 |  |  | — |  |  | — |
Department of Defense | 754,853 |  |  | 43 |  |  | — |  |  | — |  |  | — |  |  | — |
All other, including affiliated entities | 732,936 |  |  | 41 |  |  | 870,237 |  |  | 12 |  |  | 917,053 |  |  | 22 |
Total revenue | $ | 1,774,758 |  |  | 100 | % | 1 | $ | 7,411,220 |  |  | 100 | % |  | $ | 4,111,930 |  |  | 100 | %

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- Definition Tabular disclosure of entity-wide revenues from external customers for each product or service or each group of similar products or services if the information is not provided as part of the reportable operating segment information. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 40 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e9031-108599 + Details
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