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Goodwill and Intangible Assets
12 Months Ended
Dec. 31, 2021
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets Goodwill and Intangible Assets
The following sets forth goodwill and intangible assets by major asset class:
 
 December 31, 2021December 31, 2020
 Weighted Average Useful
Life
(Yrs)
GrossAccumulated
Amortization
Net Book
Value
GrossAccumulated
Amortization
Net Book
Value
Indefinite lived:
Goodwill$10,513,371 $— $10,513,371 $10,513,371 $— $10,513,371 
Definite lived:
Licenses101,323,761 (1,305,600)18,161 1,323,761 (1,276,852)46,909 
Bioject (a)125,100,000 (2,735,556)2,364,444 5,100,000 (2,468,889)2,631,111 
Other (b)184,050,000 (3,806,250)243,750 4,050,000 (3,581,250)468,750 
Total intangible assets1110,473,761 (7,847,406)2,626,355 10,473,761 (7,326,991)3,146,770 
Total goodwill and intangible assets$20,987,132 $(7,847,406)$13,139,726 $20,987,132 $(7,326,991)$13,660,141 

(a)Bioject intangible assets represent the estimated fair value of developed technology and intellectual property which were recorded from an asset acquisition.
(b)Other intangible assets represent the estimated fair value of acquired intellectual property.
Aggregate amortization expense on intangible assets was $520,000, $547,000 and $1.1 million for the years ended December 31, 2021, 2020 and 2019, respectively. Amortization expense related to intangible assets at December 31, 2021 is expected to be incurred as follows:
 
Year ending December 31,
2022$493,000 
2023276,000 
2024253,000 
2025253,000 
2026253,000 
Thereafter1,098,000 
$2,626,000 

There were no impairment or impairment indicators present and no losses were recorded during the years ended December 31, 2021, 2020 and 2019, respectively.