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Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)
Total
Adjustment
Preferred stock
Common stock
Additional paid-in capital
Additional paid-in capital
Adjustment
Accumulated deficit
Accumulated deficit
Adjustment
Accumulated other comprehensive income (loss)
Beginning balance (in shares) at Dec. 31, 2020     9 186,851,493          
Beginning balance at Dec. 31, 2020 $ 461,140,758   $ 0 $ 186,851 $ 1,367,406,869   $ (906,196,812)   $ (256,150)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Issuance of common stock for cash, net of financing costs (in shares)       20,355,000          
Issuance of common stock for cash, net of financing costs 162,105,030     $ 20,355 162,084,675        
Conversion of December 2019 Bonds to common stock (in shares)       1,009,450          
Conversion of December 2019 Bonds to common stock 4,377,892     $ 1,009 4,376,883        
Exercise of stock options for cash and vesting of RSUs, net of tax payments (in shares)       1,118,093          
Exercise of stock options for cash and vesting of RSUs, net of tax payments (1,201,789)     $ 1,118 (1,202,907)        
Stock-based compensation 9,595,947       9,595,947        
Net loss (54,402,131)           (54,402,131)    
Unrealized gain (loss) on short-term investments, net of tax 4,861               4,861
Foreign currency translation (14,419)               (14,419)
Ending balance at Mar. 31, 2021 581,606,149   $ 0 $ 209,333 1,542,261,467   (960,598,943)   (265,708)
Ending balance (in shares) at Mar. 31, 2021     9 209,334,036          
Beginning balance (in shares) at Dec. 31, 2020     9 186,851,493          
Beginning balance at Dec. 31, 2020 461,140,758   $ 0 $ 186,851 1,367,406,869   (906,196,812)   (256,150)
Ending balance at Dec. 31, 2021 $ 399,669,421 $ (1,468,216) $ 0 $ 217,382 1,609,589,797 $ (3,294,019) (1,209,855,522) $ 1,825,803 (282,236)
Ending balance (in shares) at Dec. 31, 2021     9 217,382,887          
Increase (Decrease) in Stockholders' Equity [Roll Forward]                  
Accounting Standards Update [Extensible Enumeration] Accounting Standards Update 2020-06                
Issuance of common stock for cash, net of financing costs (in shares)       8,480,483          
Issuance of common stock for cash, net of financing costs $ 29,364,538     $ 8,481 29,356,057        
Exercise of stock options for cash and vesting of RSUs, net of tax payments (in shares)       647,350          
Exercise of stock options for cash and vesting of RSUs, net of tax payments (942,521)     $ 646 (943,167)        
Stock-based compensation 7,711,151       7,711,151        
Net loss (79,073,719)           (79,073,719)    
Unrealized gain (loss) on short-term investments, net of tax (169,097)               (169,097)
Foreign currency translation (6,555)               (6,555)
Ending balance at Mar. 31, 2022 $ 355,085,002   $ 0 $ 226,509 $ 1,642,419,819   $ (1,287,103,438)   $ (457,888)
Ending balance (in shares) at Mar. 31, 2022     9 226,510,720