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Related Party Transactions (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Nov. 30, 2016 | Mar. 31, 2016 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021 | Dec. 31, 2021 | Dec. 31, 2020
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |
Revenue from related parties |  |  | $ 784,395 | $ 272,824 | $ 983,469 | $ 643,945 |  |
Collaborative agreement, amended amount |  |  |  |  |  |  | $ 13,600,000 |
Collaborative agreement, awarded exercised amount |  |  | 3,300,000 |  | 3,300,000 |  |  |
Prepaid balance |  |  | 433,000 |  | 433,000 |  |  |
Revenue under collaborative research and development arrangements with affiliated entities |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |
Revenue from related parties |  |  | 6,214 | 74,787 | 15,056 | 124,736 |  |
Director |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |
Accounts receivable |  |  | 6,800,000 |  | 6,800,000 |  | 2,600,000 |
Expenses to reimburse |  | $ 3,100,000 |  |  |  |  | $ 1,900,000 |
Term |  | 5 years |  |  |  |  | 2 years |
Awarded amount | $ 6,100,000 |  |  |  |  |  |  |
Contra-research and development expense |  |  | 3,900,000 | 381,000 | 5,400,000 | 610,000 |  |
Operating expenses related to affiliated entity |  |  | 444,000 | $ 1,200,000 | 626,000 | $ 1,600,000 |  |
Accounts payable/accrued liabilities |  |  | 1,300,000 |  | 1,300,000 |  | $ 548,000 |
Deferred grant funding, from affiliate |  |  | 154,000 |  | 154,000 |  |  |
The Wistar Institute |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |
Awarded amount |  |  |  |  |  |  |  | $ 10,700,000
Awarded option amount |  |  |  |  | 6,000,000 |  |  |
Plumbline Life Sciences |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |
Accounts receivable |  |  | $ 40,000 |  | $ 40,000 |  | $ 25,000 |
Plumbline Life Sciences | Available-for-sale Securities |  |  |  |  |  |  |  |
Related Party Transaction [Line Items] |  |  |  |  |  |  |  |
Investment owned (in shares) |  |  | 597,808 |  | 597,808 |  |  |
Ownership percentage |  |  | 18.70% |  | 18.70% |  |  |

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