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Related Party Transactions (Details) - USD ($)
 1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Nov. 30, 2016
Mar. 31, 2016
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Related Party Transaction [Line Items]                
Revenue from related parties     $ 784,395 $ 272,824 $ 983,469 $ 643,945    
Collaborative agreement, amended amount             $ 13,600,000  
Collaborative agreement, awarded exercised amount     3,300,000   3,300,000      
Prepaid balance     433,000   433,000      
Revenue under collaborative research and development arrangements with affiliated entities                
Related Party Transaction [Line Items]                
Revenue from related parties     6,214 74,787 15,056 124,736    
Director                
Related Party Transaction [Line Items]                
Accounts receivable     6,800,000   6,800,000   2,600,000  
Expenses to reimburse   $ 3,100,000         $ 1,900,000  
Term   5 years         2 years  
Awarded amount $ 6,100,000              
Contra-research and development expense     3,900,000 381,000 5,400,000 610,000    
Operating expenses related to affiliated entity     444,000 $ 1,200,000 626,000 $ 1,600,000    
Accounts payable/accrued liabilities     1,300,000   1,300,000   $ 548,000  
Deferred grant funding, from affiliate     154,000   154,000      
The Wistar Institute                
Related Party Transaction [Line Items]                
Awarded amount               $ 10,700,000
Awarded option amount         6,000,000      
Plumbline Life Sciences                
Related Party Transaction [Line Items]                
Accounts receivable     $ 40,000   $ 40,000   $ 25,000  
Plumbline Life Sciences | Available-for-sale Securities                
Related Party Transaction [Line Items]                
Investment owned (in shares)     597,808   597,808      
Ownership percentage     18.70%   18.70%