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Commitments and Contingencies - Narrative (Details) $ in Thousands	3 Months Ended			9 Months Ended
	Sep. 30, 2022 USD ($)	Sep. 30, 2021 USD ($)	Dec. 31, 2019 ft² agreement	Sep. 30, 2022 USD ($) ft²	Sep. 30, 2021 USD ($)	Jul. 31, 2022 USD ($)	Mar. 09, 2021 USD ($)
Lessee, Lease, Description [Line Items]
Lease cost	$ 858	$ 852		$ 2,500	$ 2,500
Number of agreements | agreement			2
McDermid v. Inovio Pharmaceuticals, Inc. and J. Joseph Kim
Lessee, Lease, Description [Line Items]
Estimate of cash settlement						$ 30,000	$ 30,000
Estimate of shares settlement						$ 14,000	$ 14,000
Minimum
Lessee, Lease, Description [Line Items]
Operating lease, remaining lease term	1 year 2 months 12 days			1 year 2 months 12 days
Maximum
Lessee, Lease, Description [Line Items]
Operating lease, remaining lease term	7 years 3 months 18 days			7 years 3 months 18 days
San Diego, California
Lessee, Lease, Description [Line Items]
Area leased (in square feet) | ft²				82,200
Plymouth Meeting, Pennsylvania
Lessee, Lease, Description [Line Items]
Area leased (in square feet) | ft²			13,500	57,360

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