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Related Party Transactions (Details) - USD ($) $ in Thousands	1 Months Ended		12 Months Ended
	Nov. 30, 2016	Mar. 31, 2016	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Agreement amended amount				$ 13,600
Awarded exercised amount			$ 3,300
Plumbline Life Sciences
Related Party Transaction [Line Items]
Number of shares owned (in shares)			597,808	597,808
Ownership percentage			18.70%	18.90%
PLS (affiliated entity)
Related Party Transaction [Line Items]
Revenue from related parties			$ 34	$ 245	$ 1,400
Accounts receivable			59	25
The Wistar Institute
Related Party Transaction [Line Items]
Accounts receivable			9,900	2,600
Expenses to reimburse		$ 3,100
Term		5 years
Awarded amount					10,700
Awarded option amount			6,000
Operating expenses related to affiliated entity			1,400	2,900	$ 2,300
Due to related parties			1,200	548
Prepaid expense			375	261
Deferred grant funding from affiliate			88	37
Director
Related Party Transaction [Line Items]
Expenses to reimburse				1,900
Awarded amount	$ 6,100
Grant proceeds received			$ 8,700	$ 3,000

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