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Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2022

Accounting Policies [Abstract]

Summary Of Common Shares That Were Excluded From The Diluted Net Loss Per Share Calculation Because Of Their Anti-Dilutive Effect

The following table summarizes potential shares of common stock that were excluded from diluted net loss per share calculation because of their anti-dilutive effect:

			Year Ended December 31,
			2022						2021						2020
Options to purchase common stock			12,221,548						10,488,993						8,906,624
Service-based restricted stock units			2,556,257						2,448,868						2,558,052
Performance-based restricted stock units			111,941						663,353						663,353
Convertible preferred stock			3,309						3,309						3,309
Convertible notes			3,049,980						3,049,980						3,049,980
December 2019 Bonds			—						—						1,009,450
Total			17,943,035						16,654,503						16,190,768

Summary Of Assumptions Used To Estimate The Fair Value Of Stock Options

The weighted average assumptions used in the Black-Scholes model for option grants to employees and directors are presented below:

			Year Ended December 31,
			2022						2021						2020
Risk-free interest rate			2.05%						0.91%						0.63%
Expected volatility			94%						93%						78%
Expected life in years			5.7						6						6
Dividend yield			—						—						—

The weighted average assumptions used in the Black-Scholes model for option grants to non-employees are presented below:

			Year Ended December 31,
			2022						2021						2020
Risk-free interest rate			1.96%						1.45%						0.82%
Expected volatility			87%						87%						76%
Expected life in years			10						10						10
Dividend yield			—						—						—

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- Definition

Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI https://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257

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- Definition

Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (f)(2)
-URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901

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