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Summary of Significant Accounting Policies - Narrative (Details)
 12 Months Ended
Dec. 31, 2022
USD ($)
segment
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Property, Plant and Equipment [Line Items]      
Net loss from operations $ 279,818,065 $ 303,658,710 $ 166,411,157
Working capital 218,400,000    
Accumulated deficit 1,487,847,784 1,209,855,522  
Cash, cash equivalents, and short-term investments 253,000,000    
Proceeds from issuance of common stock $ 82,955,311 209,441,410 454,486,400
Number of operating segments | segment 1    
Allowance for doubtful accounts $ 0 0  
Finite lived intangible assets, net 2,129,861 2,626,355  
Deferred tax assets, valuation allowance $ 299,124,000 237,205,000  
Minimum      
Property, Plant and Equipment [Line Items]      
Property, plant, and equipment, useful life 3 years    
Intangible asset, useful life 2 years    
Maximum      
Property, Plant and Equipment [Line Items]      
Property, plant, and equipment, useful life 5 years    
Intangible asset, useful life 18 years    
Common stock | Sales Agreement      
Property, Plant and Equipment [Line Items]      
Proceeds from issuance of common stock $ 83,000,000 47,700,000 $ 454,500,000
Common stock | Underwritten Public Offering      
Property, Plant and Equipment [Line Items]      
Proceeds from issuance of common stock   $ 162,100,000