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Collaborative Agreements (Details) - USD ($)
 1 Months Ended 12 Months Ended
Apr. 11, 2018
Jan. 31, 2022
Jan. 31, 2021
Jun. 30, 2020
Apr. 30, 2020
Mar. 31, 2020
Jan. 31, 2020
Aug. 30, 2019
Oct. 31, 2018
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Revenue from collaborative arrangements and other contracts, including affiliated entity                   $ 10,262,268 $ 1,774,758 $ 7,411,220
Advaccine                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Revenue from collaborative arrangements and other contracts, including affiliated entity                   0 0 5,000,000
Advaccine | Collaborative Arrangement                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Upfront payment received     $ 3,000,000             1,200,000 4,500,000 0
Additional revenue to be achieved                   $ 200,000,000    
Obligation period to pay royalties                   10 years    
Annual maintenance                   $ 1,500,000    
Annual maintenance period                   5 years    
Agreement, number of days written notice before termination                   18 months    
Collaboration agreement, payment earned                     2,000,000  
Revenue from collaborative arrangements and other contracts, including affiliated entity                     5,000,000  
Advaccine | Collaborative Arrangement | Revenue under collaborative research and development arrangements                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Revenue from collaborative arrangements and other contracts, including affiliated entity                   $ 0 0 5,000,000
ApolloBio | Collaborative Arrangement                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Additional revenue to be achieved                   $ 20,000,000    
Obligation period to pay royalties                   10 years    
Agreement, number of days written notice before termination                   90 days    
Agreement period from effective date for termination                   1 year    
Coalition for Epidemic Preparedness Innovations | Collaborative Arrangement                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Upfront payment received                   $ 6,700,000 10,000,000 6,400,000
Collaborative agreement, funding to be received $ 56,000,000       $ 6,900,000              
Collaborative agreement, period to receive funding for research and development 5 years                      
Coalition for Epidemic Preparedness Innovations | Collaborative Arrangement | Lassa Fever And MERS Vaccine                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Accounts receivable                   1,700,000 1,900,000  
Coalition for Epidemic Preparedness Innovations | Collaborative Arrangement | COVID19 Vaccine                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Collaborative agreement, funding to be received             $ 9,000,000     1,100,000 6,900,000 10,000,000
Grants receivable                   2,300,000 1,800,000  
Coalition for Epidemic Preparedness Innovations | Collaborative Arrangement | CELLECTRA 3PSP Proprietary Smart Device                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Collaborative agreement, funding to be received         5,000,000              
Coalition for Epidemic Preparedness Innovations | Collaborative Arrangement | IN O4800                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Collaborative agreement, funding to be received         $ 1,300,000              
Bill And Melinda Gates Foundation | Collaborative Arrangement | CELLECTRA 3PSP Proprietary Smart Device                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Collaborative agreement, funding to be received           $ 5,000,000       0 893,000 4,100,000
Bill And Melinda Gates Foundation | Collaborative Arrangement | D N A Encoded Monoclonal Antibody Technology                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Collaborative agreement, funding to be received               $ 1,100,000 $ 2,200,000 233,000 182,000 463,000
Grants receivable                   153,000 384,000  
Department Of Defence | Collaborative Arrangement                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Procurement contract                   9,600,000 755,000 0
Grant proceeds received                   $ 6,100,000 $ 27,100,000 $ 21,200,000
Department Of Defence | Collaborative Arrangement | CELLECTRA 3PSP Proprietary Smart Device                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Funding received       $ 54,500,000                
Purchase price, procurement contract   $ 10,700,000   $ 16,800,000