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Commitments and Contingencies - Narrative (Details) $ in Millions	3 Months Ended	12 Months Ended
	Dec. 31, 2019 ft² agreement	Dec. 31, 2022 USD ($) ft²	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Jul. 31, 2022 USD ($)	Mar. 09, 2021 USD ($)
Operating Leased Assets [Line Items]
Lessee, operating lease, area of land under lease | ft²	13,500
Lease, cost | $		$ 3.4	$ 3.4	$ 3.4
Number of lease agreements entered into | agreement	2
McDermid v. Inovio Pharmaceuticals, Inc. and J. Joseph Kim
Operating Leased Assets [Line Items]
Estimate of cash settlement | $					$ 30.0	$ 30.0
Estimate of shares settlement | $					$ 14.0	$ 14.0
Minimum
Operating Leased Assets [Line Items]
Operating lease, remaining lease term		10 months 24 days
Maximum
Operating Leased Assets [Line Items]
Operating lease, remaining lease term		7 years
San Diego, California
Operating Leased Assets [Line Items]
Lessee, operating lease, area of land under lease | ft²		82,200
Plymouth Meeting, Pennsylvania
Operating Leased Assets [Line Items]
Lessee, operating lease, area of land under lease | ft²		57,360

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