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Stock-Based Compensation - Narrative (Details) - USD ($) | 3 Months Ended
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Mar. 31, 2023 | Mar. 31, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Non-cash stock-based compensation | $ 3,809,003 | $ 7,711,151
Total unrecognized compensation cost related to unvested stock options | $ 10,500,000 |
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years) | 1 year 8 months 12 days |
Weighted average grant date fair value (in dollars per share) | $ 0.97 | $ 2.48
J. Joseph Kim |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Settled in shares percentage | 50.00% |
Settled in cash percentage | 50.00% |
Employees and Directors |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Non-cash stock-based compensation | $ 3,600,000 | $ 7,200,000
Employees and Directors | Research and Development Expense |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Allocated share-based compensation expense | 1,500,000 | 3,700,000
Employees and Directors | General and Administrative Expense |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Allocated share-based compensation expense | 2,100,000 | 3,500,000
Non Employee |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Non-cash stock-based compensation | 220,000 | $ 550,000
Restricted Stock Units |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |
Total unrecognized compensation cost related to unvested stock options | $ 6,100,000 |
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years) | 1 year 8 months 12 days |
Weighted average grant date fair value, restricted stock units (in dollars per share) | $ 1.20 | $ 3.33

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Weighted-average period over which cost not yet recognized is expected to be recognized for award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2)(iii)(01) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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