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Commitments and Contingencies - Narrative (Details)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
USD ($)
ft²
shares
Mar. 31, 2022
USD ($)
Dec. 31, 2019
ft²
agreement
Feb. 28, 2023
shares
Jul. 31, 2022
USD ($)
Mar. 09, 2021
USD ($)
Lessee, Lease, Description [Line Items]            
Lease cost $ 840 $ 830        
Number of agreements | agreement     2      
Common stock, shares, issued (in shares) | shares 262,739,126          
McDermid v. Inovio Pharmaceuticals, Inc. and J. Joseph Kim            
Lessee, Lease, Description [Line Items]            
Estimate of cash settlement         $ 30,000 $ 30,000
Estimate of shares settlement         $ 14,000 $ 14,000
Common stock, shares, issued (in shares) | shares       9,121,000    
Minimum            
Lessee, Lease, Description [Line Items]            
Operating lease, remaining lease term 8 months 12 days          
Maximum            
Lessee, Lease, Description [Line Items]            
Operating lease, remaining lease term 6 years 9 months 18 days          
San Diego, California            
Lessee, Lease, Description [Line Items]            
Area leased (in square feet) | ft² 82,200          
Plymouth Meeting, Pennsylvania            
Lessee, Lease, Description [Line Items]            
Area leased (in square feet) | ft² 57,360   13,500