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Stock-Based Compensation - Narrative (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Non-cash stock-based compensation     $ 6,727,000 $ 16,047,204
Total unrecognized compensation cost related to unvested stock options $ 8,700,000   $ 8,700,000  
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years)     1 year 7 months 6 days  
Weighted average grant date fair value (in dollars per share) $ 0.60 $ 1.66 $ 0.94 $ 2.35
J. Joseph Kim        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Settled in cash percentage     50.00%  
Settled in shares percentage     50.00%  
Employees and Directors        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Non-cash stock-based compensation $ 2,800,000 $ 8,800,000 $ 6,400,000 $ 16,000,000
Employees and Directors | Research and Development Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated share-based compensation expense 1,300,000 2,200,000 2,700,000 5,900,000
Employees and Directors | General and Administrative Expense        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Allocated share-based compensation expense 1,500,000 6,600,000 3,700,000 10,100,000
Non Employee        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Non-cash stock-based compensation 146,000 $ 415,000 366,000 $ 965,000
Restricted Stock Units        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Total unrecognized compensation cost related to unvested stock options $ 6,300,000   $ 6,300,000  
Period over which total unrecognized compensation cost related to unvested stock options will be recognized (in years)     1 year 8 months 12 days  
Weighted average grant date fair value, restricted stock units (in dollars per share) $ 0.77 $ 2.14 $ 0.86 $ 3.12