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Basis of Presentation, Liquidity and Risks and Uncertainties (Details) - USD ($)
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                  
Net loss $ 33,929,864 $ 35,534,533 $ 40,649,317 $ 37,783,896 $ 108,497,311 $ 79,073,719 $ 110,113,714 $ 225,354,926  
Working capital 131,100,000           131,100,000    
Accumulated deficit 1,597,961,498           1,597,961,498   $ 1,487,847,784
Cash, cash equivalents, and short-term investments $ 167,500,000           167,500,000    
Proceeds from issuance of stock             3,623,462 $ 76,287,314  
Common stock | Sales Agreements                  
New Accounting Pronouncements or Change in Accounting Principle [Line Items]                  
Proceeds from issuance of stock             $ 3,600,000   $ 83,000,000