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Related Party Transactions (Details) - USD ($)	1 Months Ended		3 Months Ended		9 Months Ended		12 Months Ended
	Dec. 31, 2022	Mar. 31, 2016	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Revenue from related parties			$ 388,446	$ 9,154,133	$ 729,359	$ 10,137,602
Research and development expenses			$ 15,503,032	33,087,130	$ 69,423,513	145,530,626
Plumbline Life Sciences
Related Party Transaction [Line Items]
Investment owned (in shares)			597,808		597,808
Non-controlling interest			17.80%		17.80%
Affiliated Entity
Related Party Transaction [Line Items]
Expenses to reimburse		$ 3,100,000
Term		5 years
Contra-research and development expense			$ 316,000	824,000	$ 705,000	6,300,000
Affiliated Entity | Revenue under collaborative research and development arrangements with affiliated entities
Related Party Transaction [Line Items]
Revenue from related parties			0	7,000	0	22,000
Plumbline Life Sciences | Affiliated Entity
Related Party Transaction [Line Items]
Accounts receivable	$ 59,000		59,000		59,000
The Wistar Institute
Related Party Transaction [Line Items]
Collaborative agreement, amended amount							$ 13,600,000
The Wistar Institute | Affiliated Entity
Related Party Transaction [Line Items]
Accounts receivable	9,900,000		2,100,000		2,100,000
Awarded amount	1,200,000							$ 10,700,000
Awarded option amount	5,400,000						$ 1,600,000
Research and development expenses			407,000	$ 474,000	1,300,000	$ 1,400,000
Accounts payable and accrued liabilities, current	$ 1,200,000		712,000		712,000
Deferred grant funding, from affiliate			22,000		22,000
Prepaid balance			$ 35,000		$ 35,000

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