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Summary of Significant Accounting Policies - Narrative (Details)
 3 Months Ended 12 Months Ended
Jan. 24, 2024
Sep. 30, 2023
USD ($)
Jun. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
segment
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Property, Plant and Equipment [Line Items]            
Net loss from operations       $ 135,117,352 $ 279,818,065 $ 303,658,710
Working capital       110,500,000    
Accumulated deficit       1,622,965,136 1,487,847,784  
Cash, cash equivalents, and short-term investments       145,300,000    
Proceeds from issuance of common stock       $ 5,461,745 82,955,311 209,441,410
Number of operating segments | segment       1    
Allowance for doubtful accounts       $ 0 0  
Impairment of goodwill   $ 10,500,000   10,513,371 0 0
Valuation allowance       (327,493,000) (299,124,000)  
Impairment of intangible assets       $ 1,984,444 0 0
Bioject            
Property, Plant and Equipment [Line Items]            
Impairment of intangible assets     $ 2,000,000      
Subsequent Event            
Property, Plant and Equipment [Line Items]            
Stock split, conversion ratio 0.083333          
Minimum            
Property, Plant and Equipment [Line Items]            
Property, plant, and equipment, useful life       3 years    
Maximum            
Property, Plant and Equipment [Line Items]            
Property, plant, and equipment, useful life       5 years    
Common stock | Sales Agreement            
Property, Plant and Equipment [Line Items]            
Proceeds from issuance of common stock       $ 5,500,000 $ 83,000,000 47,700,000
Common stock | Underwritten Public Offering            
Property, Plant and Equipment [Line Items]            
Proceeds from issuance of common stock           $ 162,100,000