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Basis of Presentation, Liquidity and Risks and Uncertainties (Details)
 1 Months Ended 3 Months Ended 12 Months Ended
Apr. 18, 2024
USD ($)
$ / shares
shares
Jan. 24, 2024
Jan. 31, 2024
Mar. 31, 2024
USD ($)
$ / shares
Mar. 31, 2023
USD ($)
Dec. 31, 2023
USD ($)
$ / shares
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Net loss       $ 30,469,871 $ 40,649,317  
Working capital       88,300,000    
Accumulated deficit       $ 1,653,435,007   $ 1,622,965,136
Common stock, par value (in dollars per share) | $ / shares       $ 0.001   $ 0.001
Cash, cash equivalents, and short-term investments       $ 105,600,000    
Proceeds from issuance of stock       $ 5,225,133 $ 0 $ 5,500,000
Stock split, conversion ratio   0.083333 0.083333      
Underwritten Registered Direct Offering | Subsequent Event            
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Proceeds from sale of stock $ 33,200,000          
Underwritten Registered Direct Offering | Common stock | Subsequent Event            
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Number of shares issued in transaction (in shares) | shares 2,536,258          
Common stock, par value (in dollars per share) | $ / shares $ 0.001          
Sale of stock, price per share (in dollars per share) | $ / shares $ 7.693          
Underwritten Registered Direct Offering | Warrant | Subsequent Event            
New Accounting Pronouncements or Change in Accounting Principle [Line Items]            
Number of shares issued in transaction (in shares) | shares 2,135,477          
Sale of stock, price per share (in dollars per share) | $ / shares $ 7.692          
Warrant exercise price (in dollars per share) | $ / shares $ 0.001