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Net Loss Per Share
 9 Months Ended
Sep. 30, 2024
Earnings Per Share [Abstract]  
Net Loss Per Share Net Loss Per Share
Basic net loss per share is computed by dividing the net loss for the period by the weighted average number of shares of common stock outstanding during the period. The outstanding Pre-Funded Warrants (see Note 7) are included in the weighted-average common shares outstanding in the basic net loss per share calculation for the three and nine months ended September 30, 2024 given their nominal exercise price.
Diluted net loss per share is calculated in accordance with the treasury stock method for the outstanding stock options and RSUs and reflects the potential dilution that would occur if securities or other contracts to issue common stock were exercised or converted to common stock. The dilutive impact of the Notes previously issued by the Company (discussed in Note 6) was considered using the "if-converted" method. The calculation of diluted net loss per share requires that, to the extent the average market price of the underlying shares for the reporting period exceeds the exercise price of the options or other securities and the presumed exercise of such securities are dilutive to net loss per share for the period, an adjustment to the net loss used in the calculation is required to remove the change in fair value of such securities from the numerator for the period. Likewise, an adjustment to the denominator is required to reflect the related dilutive shares, if any. For the three and nine months ended September 30, 2024 and 2023, basic and diluted net loss per share were the same, as the assumed exercise or settlement of stock options, service-based RSUs, performance-and market-based RSUs and the potentially dilutive shares issuable upon conversion of the Notes prior to their repayment on March 1, 2024 would have been anti-dilutive.
Basic and diluted net loss per share for the three and nine months ended September 30, 2024 and 2023 are calculated as follows:
Three Months Ended September 30,
20242023
Numerator:
    Net loss$(25,165,478)$(33,929,864)
Denominator:
     Shares used to compute net loss per share, basic and diluted
          Weighted-average common shares outstanding26,005,020 22,385,229 
          Weighted-average pre-funded warrants2,135,477 — 
     Weighted-average common shares outstanding used to compute basic and diluted net loss per share28,140,497 22,385,229 
Net loss per share
     Basic and diluted$(0.89)$(1.52)
Nine Months Ended September 30,
20242023
Numerator:
    Net loss$(87,872,447)$(110,113,714)
Denominator:
     Shares used to compute net loss per share, basic and diluted
          Weighted-average common shares outstanding24,923,227 21,986,840 
          Weighted-average pre-funded warrants1,293,756 — 
     Weighted-average common shares outstanding used to compute basic and diluted net loss per share26,216,983 21,986,840 
Net loss per share
     Basic and diluted$(3.35)$(5.01)

The following table summarizes potential shares of common stock that were excluded from the diluted net loss per share calculation because of their anti-dilutive effect:
Three and Nine Months Ended September 30
20242023
Options to purchase common stock1,319,769 1,209,989 
Service-based restricted stock units326,108 277,440 
Performance-and market-based restricted stock units
83,800 — 
Convertible preferred stock275 275 
Convertible notes— 254,165 
Total1,729,952 1,741,869