<SEC-DOCUMENT>0001055726-24-000004.txt : 20240228
<SEC-HEADER>0001055726-24-000004.hdr.sgml : 20240228
<ACCEPTANCE-DATETIME>20240228170753
ACCESSION NUMBER:		0001055726-24-000004
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20240226
FILED AS OF DATE:		20240228
DATE AS OF CHANGE:		20240228

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Humeau Laurent
		CENTRAL INDEX KEY:			0001770390
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14888
		FILM NUMBER:		24696713

	MAIL ADDRESS:	
		STREET 1:		C/O INOVIO PHARMACEUTICALS, INC.
		STREET 2:		660 W. GERMANTOWN PIKE, SUITE 110
		CITY:			PLYMOUTH MEETING
		STATE:			PA
		ZIP:			19462

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			INOVIO PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001055726
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		IRS NUMBER:				330969592
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		6769 MESA RIDGE RD.
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		8584103134

	MAIL ADDRESS:	
		STREET 1:		6769 MESA RIDGE RD.
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INOVIO BIOMEDICAL CORP
		DATE OF NAME CHANGE:	20050404

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GENETRONICS BIOMEDICAL CORP
		DATE OF NAME CHANGE:	20011116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GENETRONICS BIOMEDICAL LTD
		DATE OF NAME CHANGE:	19980213
</SEC-HEADER>
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<TYPE>4
<SEQUENCE>1
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<DESCRIPTION>FORM 4
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        <issuerName>INOVIO PHARMACEUTICALS, INC.</issuerName>
        <issuerTradingSymbol>INO</issuerTradingSymbol>
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            <rptOwnerName>Humeau Laurent</rptOwnerName>
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            <rptOwnerStreet1>C/O INOVIO PHARMACEUTICALS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>6769 MESA RIDGE RD.</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92121</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Scientific Officer</officerTitle>
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    <derivativeTable>
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            <expirationDate>
                <footnoteId id="F1"/>
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            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
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                    <footnoteId id="F2"/>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
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                    <footnoteId id="F2"/>
                </underlyingSecurityShares>
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        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Common Stock Option</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.46</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2024-02-28</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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            <transactionAmounts>
                <transactionShares>
                    <value>18750</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2024-02-28</value>
                <footnoteId id="F6"/>
            </exerciseDate>
            <expirationDate>
                <value>2034-02-28</value>
            </expirationDate>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>18750</value>
                </underlyingSecurityShares>
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                <sharesOwnedFollowingTransaction>
                    <value>18750</value>
                </sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
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        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Restricted Stock Unit</value>
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            <conversionOrExercisePrice>
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            </conversionOrExercisePrice>
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                <value>2024-02-28</value>
            </transactionDate>
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                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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            <transactionAmounts>
                <transactionShares>
                    <value>15029</value>
                </transactionShares>
                <transactionPricePerShare>
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                    <value>A</value>
                </transactionAcquiredDisposedCode>
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                <footnoteId id="F7"/>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                <underlyingSecurityShares>
                    <value>15029</value>
                </underlyingSecurityShares>
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                <sharesOwnedFollowingTransaction>
                    <value>15029</value>
                </sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
                    <value>D</value>
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        </derivativeTransaction>
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    <footnotes>
        <footnote id="F1">Each restricted stock unit represents a contingent right to receive one share of common stock.  The vesting schedule for the 5,635 restricted stock units was as follows: 1,879 shares vested on February 26, 2022; 1,878 shares vested on February 26, 2023; and 1,878 shares vested on February 26, 2024.  Vested restricted stock units could be settled in shares of common stock, cash or a combination of both.</footnote>
        <footnote id="F2">Gives effect to a 1-for-12 reverse stock split effected by the Issuer on January 24, 2024.</footnote>
        <footnote id="F3">The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in the immediately preceding row and described in footnote (1) herein.</footnote>
        <footnote id="F4">Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 11,566 restricted stock units is as follows: 3,855 shares vested on February 26, 2023; 3,856 shares vested on February 26, 2024; and 3,855 shares will vest on February 26, 2025. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.</footnote>
        <footnote id="F5">The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in the immediately preceding row and described in footnote (4) herein.</footnote>
        <footnote id="F6">The vesting schedule for the 18,750 options is as follows: 4,688 shares vested on February 28, 2024; 4,688 shares will vest on February 28, 2025; 4,687 shares will vest on February 28, 2026; and 4,687 shares will vest on February 28, 2027.</footnote>
        <footnote id="F7">Each restricted stock unit represents a contingent right to receive one share of common stock.  The vesting schedule for the 15,029 restricted stock units is as follows: 5,010 shares will vest on February 26, 2025; 5,010 shares will vest on February 26, 2026; and 5,009 shares will vest on February 26, 2027.  Vested restricted stock units can be settled in shares of common stock, cash or a combination of both.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Laurent Humeau</signatureName>
        <signatureDate>2024-02-28</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</DOCUMENT>
</SEC-DOCUMENT>
