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Related Party Transactions (Details) - USD ($)	1 Months Ended			12 Months Ended
	Aug. 31, 2024	Dec. 31, 2022	Mar. 31, 2016	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Accounts receivable				$ 1,199,056	$ 2,405,228
Research and development				75,620,340	86,676,563
Affiliated Entity
Related Party Transaction [Line Items]
Expenses to reimburse			$ 3,100,000
Term			5 years
Grant proceeds received				482,000	1,000,000.0
Plumbline Life Sciences
Related Party Transaction [Line Items]
Accounts receivable				1,600,000	2,800,000
The Wistar Institute
Related Party Transaction [Line Items]
Agreement amended amount						$ 13,600,000
The Wistar Institute | Affiliated Entity
Related Party Transaction [Line Items]
Awarded amount		$ 1,200,000					$ 10,700,000
Agreement amended amount	$ 12,500,000			2,400,000
Awarded option amount		$ 4,200,000
Research and development				1,500,000	1,800,000
Accounts receivable				1,200,000	2,400,000
Accounts payable and accrued expenses				1,400,000	1,100,000
Prepaid expense				0	20,000
Deferred grant funding from affiliate				$ 0	$ 22,000
Plumbline Life Sciences
Related Party Transaction [Line Items]
Number of shares owned (in shares)				597,808	597,808
Ownership percentage				17.30%	17.80%

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