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v3.25.1

Condensed Consolidated Statements of Cash Flows - USD ($) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2025 | Mar. 31, 2024 | Dec. 31, 2024
Cash flows from operating activities: |  |  |
Net loss | $ (19,694,697) | $ (30,469,871) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation | 371,367 | 424,473 |
Amortization of operating lease right-of-use assets | 372,083 | 335,257 |
Change in fair value of common stock warrant liability | (3,712,872) | 0 |
Non-cash stock-based compensation | 1,399,349 | 2,525,433 |
Non-cash interest on senior convertible notes | 0 | (355,654) |
Amortization of discounts on investments | (386) | (684,651) |
Loss on sales of short-term investments | 482 | 691,168 |
(Gain) loss on equity investment in affiliated entity | (695,131) | 126,018 |
Net unrealized gain on available-for-sale equity securities | (140,234) | (500,877) |
Changes in operating assets and liabilities: |  |  |
Accounts receivable from affiliated entity | (111,181) | (145,854) |
Prepaid expenses and other current assets | 295,797 | 1,897,016 |
Accounts payable and accrued expenses, including due to affiliated entity | (4,161,751) | (3,160,238) |
Accrued clinical trial expenses | (202,623) | 657,104 |
Operating lease right-of-use assets and liabilities, net | (594,230) | (11,791) |
Grant funding liability, including from affiliated entity | 0 | (87,489) |
Net cash used in operating activities | (26,874,027) | (28,759,956) |
Cash flows from investing activities: |  |  |
Purchases of investments | 0 | (9,751,047) |
Proceeds from sale or maturity of investments | 7,620 | 55,169,260 |
Purchases of capital assets | (59,373) | (35,578) |
Net cash (used in) provided by investing activities | (51,753) | 45,382,635 |
Cash flows from financing activities: |  |  |
Repayment of convertible senior notes | 0 | (16,415,000) |
Proceeds from issuance of common stock, net of issuance costs | 1,102,149 | 5,225,133 |
Taxes paid related to net share settlement of equity awards | (74,219) | (174,248) |
Net cash provided by (used in) financing activities | 1,027,930 | (11,364,115) |
Effect of exchange rate changes on cash and cash equivalents | 0 | 32,403 |
(Decrease) Increase in cash and cash equivalents | (25,897,850) | 5,290,967 |
Cash and cash equivalents, beginning of period | 65,813,297 | 14,310,862 | $ 14,310,862
Cash and cash equivalents, end of period | 39,915,447 | 19,601,829 | $ 65,813,297
Supplemental disclosures: |  |  |
Amounts accrued for purchases of fixed assets | 0 | 442,976 |
Interest paid | $ 0 | $ 533,487 |

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