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v3.25.3

Condensed Consolidated Statements of Cash Flows - USD ($) | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2025 | Mar. 31, 2025 | Sep. 30, 2024 | Mar. 31, 2024 | Sep. 30, 2025 | Sep. 30, 2024 | Dec. 31, 2024
Cash flows from operating activities: |  |  |  |  |  |  |
Net loss | $ (45,496,672) | $ (19,694,697) | $ (25,165,478) | $ (30,469,871) | $ (88,710,781) | $ (87,872,447) |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |  |  |  |
Depreciation |  |  |  |  | 1,077,716 | 1,335,326 |
Amortization of operating lease right-of-use assets |  |  |  |  | 1,157,060 | 1,018,887 |
Change in fair value of common stock warrant liabilities | 22,515,730 |  | 0 |  | 20,680,868 | 0 |
Non-cash stock-based compensation |  |  |  |  | 2,991,227 | 5,279,344 |
Non-cash interest on senior convertible notes |  |  |  |  | 0 | (355,654) |
Amortization of discounts on investments |  |  |  |  | 50,867 | (1,510,276) |
Loss on sales of short-term investments |  |  |  |  | 890,888 | 1,278,959 |
Loss on disposal of fixed assets |  |  |  |  | 0 | 21,930 |
(Gain) loss on equity investment in affiliated entity | 589,618 |  | (324,251) |  | (881,886) | 136,061 |
Net unrealized gain on available-for-sale equity securities | (205,259) |  | (1,330,811) |  | (1,104,782) | (1,810,868) |
Changes in operating assets and liabilities: |  |  |  |  |  |  |
Accounts receivable from affiliated entity |  |  |  |  | 220,466 | 542,489 |
Prepaid expenses and other current assets |  |  |  |  | (881,069) | 796,981 |
Other assets |  |  |  |  | (32,822) | 38,900 |
Accounts payable and accrued expenses, including due to affiliated entity |  |  |  |  | (1,847,935) | (4,340,806) |
Accrued clinical trial expenses |  |  |  |  | (1,065,890) | 2,131,186 |
Operating lease right-of-use assets and liabilities, net |  |  |  |  | (1,844,960) | (993,249) |
Grant funding liability, including from affiliated entity |  |  |  |  | 42,152 | (109,407) |
Net cash used in operating activities |  |  |  |  | (69,258,881) | (84,412,644) |
Cash flows from investing activities: |  |  |  |  |  |  |
Purchases of investments |  |  |  |  | (4,946,073) | (54,138,027) |
Proceeds from sale or maturity of investments |  |  |  |  | 19,201,873 | 124,052,574 |
Purchases of capital assets |  |  |  |  | (158,254) | (487,832) |
Net cash provided by investing activities |  |  |  |  | 14,097,546 | 69,426,715 |
Cash flows from financing activities: |  |  |  |  |  |  |
Repayment of convertible senior notes |  |  |  |  | 0 | (16,415,000) |
Proceeds from issuance of common stock, net of issuance costs |  |  |  |  | 8,287,277 | 22,951,867 |
Proceeds from exercise of warrants and pre-funded warrants |  |  |  |  | 752,134 | 0 |
Proceeds from stock option exercises |  |  |  |  | 0 | 67,675 |
Taxes paid related to net share settlement of equity awards |  |  |  |  | (110,783) | (420,795) |
Net cash provided by financing activities |  |  |  |  | 25,915,458 | 22,330,144 |
Effect of exchange rate changes on cash and cash equivalents |  |  |  |  | 0 | 32,403 |
(Decrease) Increase in cash and cash equivalents |  |  |  |  | (29,245,877) | 7,376,618 |
Cash and cash equivalents, beginning of period |  | $ 65,813,297 |  | $ 14,310,862 | 65,813,297 | 14,310,862 | $ 14,310,862
Cash and cash equivalents, end of period | $ 36,567,420 |  | $ 21,687,480 |  | 36,567,420 | 21,687,480 | $ 65,813,297
Supplemental disclosures: |  |  |  |  |  |  |
Interest paid |  |  |  |  | 0 | 533,487 |
Pre-Funded Warrants |  |  |  |  |  |  |
Cash flows from financing activities: |  |  |  |  |  |  |
Proceeds from issuance of warrants, net of issuance costs |  |  |  |  | 0 | 16,146,397 |
Warrant |  |  |  |  |  |  |
Cash flows from financing activities: |  |  |  |  |  |  |
Proceeds from issuance of warrants, net of issuance costs |  |  |  |  | $ 16,986,830 | $ 0 |

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