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v3.25.3

Segment Information (Details) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 USD ($) | Jun. 30, 2025 USD ($) | Mar. 31, 2025 USD ($) | Sep. 30, 2024 USD ($) | Jun. 30, 2024 USD ($) | Mar. 31, 2024 USD ($) | Sep. 30, 2025 USD ($) segment | Sep. 30, 2024 USD ($)
Segment Reporting [Abstract] |  |  |  |  |  |  |  |
Number of reportable segments | segment |  |  |  |  |  |  | 1 |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |
Revenue from collaborative arrangement | $ 0 |  |  | $ 0 |  |  | $ 65,343 | $ 100,762
Less: |  |  |  |  |  |  |  |
Research and development expenses | 13,333,329 |  |  | 18,733,584 |  |  | 43,945,638 | 62,734,891
General and administrative | 7,877,126 |  |  | 8,613,895 |  |  | 25,465,208 | 29,395,232
Total operating expenses | 21,210,455 |  |  | 27,347,479 |  |  | 69,410,846 | 92,130,123
Interest income | 552,108 |  |  | 1,106,758 |  |  | 1,970,823 | 3,914,406
Interest expense | 0 |  |  | 0 |  |  | 0 | (177,833)
Change in fair value of common stock warrant liabilities | (22,515,730) |  |  | 0 |  |  | (20,680,868) | 0
(Loss) gain on investment in affiliated entity | (589,618) |  |  | 324,251 |  |  | 881,886 | (136,061)
Net unrealized gain on available-for-sale equity securities | 205,259 |  |  | 1,330,811 |  |  | 1,104,782 | 1,810,868
Other expense, net | (1,938,236) |  |  | (579,819) |  |  | (2,641,901) | (1,254,466)
Net loss | (45,496,672) | $ (23,519,412) | $ (19,694,697) | (25,165,478) | $ (32,237,098) | $ (30,469,871) | (88,710,781) | (87,872,447)
INO-3107 |  |  |  |  |  |  |  |
Less: |  |  |  |  |  |  |  |
Research and development expenses | 3,352,458 |  |  | 7,009,169 |  |  | 10,790,120 | 25,697,828
INO-3112 And Other Immuno-oncology |  |  |  |  |  |  |  |
Less: |  |  |  |  |  |  |  |
Research and development expenses | 1,574,238 |  |  | 1,726,382 |  |  | 4,327,081 | 5,309,964
Other programs |  |  |  |  |  |  |  |
Less: |  |  |  |  |  |  |  |
Research and development expenses | 96,971 |  |  |  |  |  | 357,884 |
Research and development: |  |  |  | (1,119,600) |  |  |  | (292,372)
Engineering and device-related |  |  |  |  |  |  |  |
Less: |  |  |  |  |  |  |  |
Research and development expenses | 4,323,775 |  |  | 5,602,688 |  |  | 14,470,247 | 14,192,615
Stock-based compensation |  |  |  |  |  |  |  |
Less: |  |  |  |  |  |  |  |
Research and development expenses | 302,249 |  |  | 590,211 |  |  | 1,177,331 | 2,240,800
Other unallocated expenses |  |  |  |  |  |  |  |
Less: |  |  |  |  |  |  |  |
Research and development expenses | 3,683,638 |  |  | 4,924,734 |  |  | 12,822,975 | 15,586,056
Reportable Segments |  |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |  |
Revenue from collaborative arrangement | 0 |  |  | 0 |  |  | 65,343 | 100,762
Less: |  |  |  |  |  |  |  |
General and administrative | 7,877,126 |  |  | 8,613,895 |  |  | 25,465,208 | 29,395,232
Total operating expenses | 21,210,455 |  |  | 27,347,479 |  |  | 69,410,846 | 92,130,123
Interest income | 552,108 |  |  | 1,106,758 |  |  | 1,970,823 | 3,914,406
Interest expense |  |  |  |  |  |  | 0 | (177,833)
Change in fair value of common stock warrant liabilities | 22,515,730 |  |  | 0 |  |  | 20,680,868 | 0
(Loss) gain on investment in affiliated entity | (589,618) |  |  | 324,251 |  |  | 881,886 | (136,061)
Net unrealized gain on available-for-sale equity securities | 205,259 |  |  | 1,330,811 |  |  | 1,104,782 | 1,810,868
Other expense, net | (1,938,236) |  |  | (579,819) |  |  | (2,641,901) | (1,254,466)
Net loss | $ (45,496,672) |  |  | $ (25,165,478) |  |  | $ (88,710,781) | $ (87,872,447)

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