<SEC-DOCUMENT>0001387131-21-005173-index.html : 20210430
<SEC-HEADER>0001387131-21-005173.hdr.sgml : 20210430
<ACCEPTANCE-DATETIME>20210430170117
ACCESSION NUMBER:		0001387131-21-005173
CONFORMED SUBMISSION TYPE:	POS EX
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20210430
DATE AS OF CHANGE:		20210430
EFFECTIVENESS DATE:		20210430

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Flaherty & Crumrine PREFERRED & INCOME OPPORTUNITY FUND INC
		CENTRAL INDEX KEY:			0000882071
		IRS NUMBER:				954355600
		STATE OF INCORPORATION:			MD
		FISCAL YEAR END:			1130

	FILING VALUES:
		FORM TYPE:		POS EX
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-252798
		FILM NUMBER:		21879329

	BUSINESS ADDRESS:	
		STREET 1:		301 E COLORADO BLVD STE 720
		STREET 2:		C/O FLAHERTY & CRUMRINE INC
		CITY:			PASADENA
		STATE:			CA
		ZIP:			91101
		BUSINESS PHONE:		(626) 795-7300

	MAIL ADDRESS:	
		STREET 1:		301 COLORADO BLVD STE 800
		STREET 2:		C/O FLAHERTY & CRUMRINE INC
		CITY:			PASADENA
		STATE:			CA
		ZIP:			91101

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Flaherty & Crumrine PREFERRED INCOME OPPORTUNITY FUND INC
		DATE OF NAME CHANGE:	20050708

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PREFERRED INCOME OPPORTUNITY FUND INC
		DATE OF NAME CHANGE:	19920929
</SEC-HEADER>
<DOCUMENT>
<TYPE>POS EX
<SEQUENCE>1
<FILENAME>pfo-posex_043021.htm
<DESCRIPTION>POST-EFFECTIVE AMENDMENT
<TEXT>
Document 1 - file: pfo-posex_043021.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(H)
<SEQUENCE>2
<FILENAME>ex99-h.htm
<DESCRIPTION>ATM SALES AGREEMENT
<TEXT>
Document 2 - file: ex99-h.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.(L)(2)
<SEQUENCE>3
<FILENAME>ex99-l2.htm
<DESCRIPTION>OPINION AND CONSENT OF VENABLE LLP
<TEXT>
Document 3 - file: ex99-l2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>ex99l2001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: ex99l2001.jpg

</DOCUMENT>
</SEC-DOCUMENT>