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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Revenue:      
Total revenues $ 103,463 $ 156,314 $ 98,024
Operating expenses:      
Cost of service revenue (486) (3,111) (10,568)
Research and development (155,528) (234,569) (186,691)
General and administrative (71,878) (78,739) (81,007)
Fair value adjustments 3,954 556 815
Operating loss (120,475) (159,549) (179,427)
Other income (expense):      
Loss on modification of debt     (1,937)
Non-operating income 5,830 37 12,571
Interest expense, net (117,626) (97,925) (61,863)
Net loss (232,271) (257,437) (230,656)
Dividends on Series A-1 convertible preferred stock (215) (213) (212)
Less: net loss attributable to non-controlling interest (5,059) (11,676) (10,582)
Net loss attributable to Agenus Inc. common stockholders $ (227,427) $ (245,974) $ (220,286)
Per common share data:      
Basic net loss attributable to Agenus Inc. common stockholders $ (10.59) $ (13.75) $ (15.64)
Diluted net loss attributable to Agenus Inc. common stockholders $ (10.59) $ (13.75) $ (15.64)
Weighted average number of Agenus Inc. common shares outstanding:      
Basic 21,473 17,894 14,087
Diluted 21,473 17,894 14,087
Other comprehensive loss:      
Foreign currency translation loss $ (443) $ (1,870) $ (577)
Other comprehensive loss (443) (1,870) (577)
Comprehensive loss (227,870) (247,844) (220,863)
Research and Development [Member]      
Revenue:      
Total revenues 482 38,764 16,975
Service Revenue [Member]      
Revenue:      
Total revenues 2,003 2,978 10,514
Royalty Sales Milestone [Member]      
Revenue:      
Total revenues     25,250
Non-Cash Royalty Revenue Related to the Sale of Future Royalties [Member]      
Revenue:      
Total revenues $ 100,978 $ 114,572 $ 45,285