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Equity (Narrative) (Details)
$ / shares in Units, $ in Thousands
 12 Months Ended
Apr. 04, 2024
Apr. 03, 2024
Dec. 31, 2024
USD ($)
$ / shares
shares
Dec. 31, 2023
USD ($)
$ / shares
shares
Dec. 31, 2022
USD ($)
$ / shares
shares
Aug. 08, 2024
shares
May 31, 2024
$ / shares
shares
May 06, 2024
$ / shares
shares
Jun. 23, 2023
shares
Nov. 30, 2022
$ / shares
Aug. 05, 2022
shares
Aug. 04, 2022
shares
Mar. 01, 2022
shares
Jul. 22, 2020
shares
Dec. 31, 2013
USD ($)
$ / shares
Class Of Stock [Line Items]                              
Common stock, shares authorized | shares     800,000,000 800,000,000             800,000,000 400,000,000      
Common stock, preferred stock, warrants, debt securities and units | $     $ 6,983   $ 2,332                    
Warrants, exercise price | $ / shares                   $ 56.8          
Common Stock [Member]                              
Class Of Stock [Line Items]                              
Shares sold at the market, shares | shares     3,632,000 4,221,000 2,257,000                    
Reverse stock split ratio, description 1-for-20 1-for-20                          
Stockholders' Equity Note, Stock Split, Conversion Ratio 0.05 0.05                          
Common Stock [Member] | Ligand Pharmaceuticals Incorporated [Member]                              
Class Of Stock [Line Items]                              
Warrants issued to purchase shars of common stock | shares             867,052 867,052              
Warrants, exercise price | $ / shares             $ 17.3 $ 17.3              
Warrants, expiration date               May 06, 2029              
B. Riley FBR, Inc. [Member] | New Sales Agreement [Member]                              
Class Of Stock [Line Items]                              
Common stock, preferred stock, warrants, debt securities and units | $     $ 300,000                        
At Market Issuance Sales Agreement [Member] | New Sales Agreement [Member]                              
Class Of Stock [Line Items]                              
Shares sold at the market, shares | shares           13,834,015                  
At Market Issuance Sales Agreement [Member] | B. Riley FBR, Inc. [Member] | New Sales Agreement [Member]                              
Class Of Stock [Line Items]                              
Shares sold at the market, shares | shares     6,725,642           9,200,000       5,000,000 5,000,000  
Net proceeds from issuance of common stock | $     $ 33,000 $ 133,200 $ 99,200                    
Shares sold at the market, shares | shares     3,600,000 4,200,000 2,300,000                    
Shares sold price per share | $ / shares     $ 9.37 $ 32.6 $ 45.4                    
Series A convertible preferred stock [Member]                              
Class Of Stock [Line Items]                              
Preferred Stock, Redemption Price Per Share | $ / shares                             $ 1,897.2
Preferred Stock, Redemption Amount | $                             $ 31,600
Preferred Stock, Liquidation Preference Per Share | $ / shares                             $ 1,000
Preferred Stock, Amount of Preferred Dividends in Arrears | $     $ 2,500 $ 2,300                      
Preferred Stock, Per Share Amounts of Preferred Dividends in Arrears | $ / shares     $ 78.46 $ 71.67