XML 61 R38.htm IDEA: XBRL DOCUMENT v3.25.2
Business, Liquidity and Basis of Presentation (Narrative) (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 6 Months Ended 12 Months Ended
Jun. 03, 2025
Aug. 11, 2025
Aug. 07, 2025
Jun. 30, 2025
Dec. 31, 2024
Mar. 31, 2025
Jun. 30, 2024
Dec. 31, 2023
Product Information [Line Items]                
Cash, cash equivalents and short term investment       $ 9,500        
Cash and cash equivalents       9,534 $ 40,437   $ 93,723 $ 76,110
Decrease in cash and cash equivalents         30,900      
Accumulated deficit       2,236,101 $ 2,182,880      
Subordinated Notes [Member]                
Product Information [Line Items]                
Debt instrument, face amount       $ 10,500        
Debt instrument, maturity date       2026-06        
Subsequent Event [Member]                
Product Information [Line Items]                
Proceeds from sale of common stock   $ 5,200 $ 5,200          
Anticipative upfornt payment   75,000            
Amount of equity investment receivable   $ 16,000            
MiNK Therapeutics, Inc.                
Product Information [Line Items]                
Cash and cash equivalents           $ 3,200    
Zydus Pharmaceuticals Inc | License Agreement [Member]                
Product Information [Line Items]                
Percentage of royalty on net sales in exchage for license 5.00%              
License agreement period 10 years              
Zydus Pharmaceuticals Inc | Purchased Assets | Purchase Agreement                
Product Information [Line Items]                
Consideration transferred in asset purchase agreement $ 75,000              
Asset purchase, contingent consideration amount $ 50,000              
Zynext Ventures USA LLC | Securities Purchase Agreement                
Product Information [Line Items]                
Number of shares issued in transaction 2,133,333              
Consideration received in transaction $ 16,000              
Sale price per share $ 7.5