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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020
Operating Expenses: |  |  |  |
Research and development | $ 3,675 | $ 3,399 | $ 12,999 | $ 9,600
General and administrative | 1,548 | 1,062 | 3,791 | 3,687
Total operating expenses | 5,223 | 4,461 | 16,790 | 13,287
Loss from operations | (5,223) | (4,461) | (16,790) | (13,287)
Other income (expense): |  |  |  |
Grant income | 3,037 | 3,192 | 12,375 | 8,146
Change in the fair value of the derivative liability |  | (112) | 2,209 | 135
Change in the fair value of the warrant liability |  | 1 |  | 33
Change in the fair value of the Simple Agreements for Future Equity | (932) |  | (1,976) |
Other income, net | 8 | 95 | 256 | 353
Gain (loss) on debt extinguishment |  |  | 443 | (129)
Interest expense, net |  | (506) | (894) | (1,222)
Total other income, net | 2,113 | 2,670 | 12,413 | 7,316
Net loss | (3,110) | (1,791) | (4,377) | (5,971)
Cumulative preferred stock dividends | (1,859) | (1,064) | (4,326) | (3,170)
Net loss attributable to common stockholders | (4,969) | (2,855) | (8,703) | (9,141)
Unrealized (loss) gain on foreign currency translation | (3) | 18 | (9) | (40)
Total comprehensive loss | $ (3,113) | $ (1,773) | $ (4,386) | $ (6,011)
Net loss per share attributable to common stockholders, basic (in dollars per share) | $ (8.12) | $ (5.31) | $ (14.87) | $ (18.34)
Net loss per share attributable to common stockholders, diluted (in dollars per share) | $ (8.12) | $ (5.31) | $ (14.87) | $ (18.34)
Weighted-average common shares outstanding, basic (in shares) | 611,680 | 537,315 | 585,320 | 498,415
Weighted-average common shares outstanding, diluted (in shares) | 611,680 | 537,315 | 585,320 | 498,415

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