<SEC-DOCUMENT>0001104659-22-115489-index.html : 20221107
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<ACCEPTANCE-DATETIME>20221107171146
ACCESSION NUMBER:		0001104659-22-115489
CONFORMED SUBMISSION TYPE:	S-1
PUBLIC DOCUMENT COUNT:		30
FILED AS OF DATE:		20221107
DATE AS OF CHANGE:		20221107

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COGNITION THERAPEUTICS INC
		CENTRAL INDEX KEY:			0001455365
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-268228
		FILM NUMBER:		221366401

	BUSINESS ADDRESS:	
		STREET 1:		2403 SIDNEY STREET
		STREET 2:		SUITE 261
		CITY:			PITTSBURGH
		STATE:			PA
		ZIP:			15203
		BUSINESS PHONE:		412-481-2210

	MAIL ADDRESS:	
		STREET 1:		2500 WESTCHESTER AVE
		CITY:			PURCHASE
		STATE:			NY
		ZIP:			10577

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	COGNITION THERAPUTICS INC
		DATE OF NAME CHANGE:	20090204
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<FILENAME>tm2226999-3_drsa.htm
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<TEXT>
Document 1 - file: tm2226999-3_drsa.htm

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<DOCUMENT>
<TYPE>EX-1.1
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<FILENAME>tm2226999d4_ex1-1.htm
<DESCRIPTION>EXHIBIT 1.1
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Document 2 - file: tm2226999d4_ex1-1.htm

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<DOCUMENT>
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<SEQUENCE>3
<FILENAME>tm2226999d4_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
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Document 3 - file: tm2226999d4_ex5-1.htm

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<DOCUMENT>
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<FILENAME>tm2226999d4_ex10-29.htm
<DESCRIPTION>EXHIBIT 10.29
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Document 4 - file: tm2226999d4_ex10-29.htm

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<FILENAME>tm2226999d4_23-1.htm
<DESCRIPTION>EXHIBIT 23.1
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Document 5 - file: tm2226999d4_23-1.htm

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<DESCRIPTION>EX-FILING FEES
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Document 6 - file: tm2226999d4_ex-filingfees.htm

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<FILENAME>lg_cognition-4c.jpg
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Document 7 - file: lg_cognition-4c.jpg

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Document 8 - file: tm2226999d1-bc_restores4clr.jpg

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Document 9 - file: tm2226999d1-bc_reverse4clr.jpg

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Document 10 - file: tm2226999d1-fc_candid4clr.jpg

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Document 11 - file: tm2226999d1-fc_receptor4clr.jpg

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Document 12 - file: tm2226999d1-fc_working4clr.jpg

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Document 13 - file: tm2226999d1-lc_correlat4clr.jpg

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Document 14 - file: tm2226999d1-lc_evidence4clr.jpg

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Document 15 - file: tm2226999d1-lc_indicate4clr.jpg

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Document 16 - file: tm2226999d1-lc_retina4clr.jpg

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Document 17 - file: tm2226999d1-lc_study4clr.jpg

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Document 18 - file: tm2226999d1-lc_treatmen4clr.jpg

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Document 19 - file: tm2226999d1-lc_volumetric4c.jpg

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Document 20 - file: tm2226999d1-ph_anatomyclr.jpg

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Document 21 - file: tm2226999d1-ph_bindingbwlr.jpg

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Document 22 - file: tm2226999d1-ph_blocks4clr.jpg

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Document 23 - file: tm2226999d1-ph_prevents4clr.jpg

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Document 24 - file: tm2226999d1-ph_slows4clr.jpg

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<FILENAME>tm2226999d1-ph_synapsesbwlr.jpg
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Document 25 - file: tm2226999d1-ph_synapsesbwlr.jpg

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<FILENAME>tm2226999d1-tbl_studies4clr.jpg
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<TEXT>
Document 26 - file: tm2226999d1-tbl_studies4clr.jpg

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<FILENAME>tm2226999d3-bc_pipe4c.jpg
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Document 27 - file: tm2226999d3-bc_pipe4c.jpg

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<FILENAME>tm2226999d3-tbl_trials4c.jpg
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Document 28 - file: tm2226999d3-tbl_trials4c.jpg

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Document 29 - file: tm2226999d4_ex10-29img01.jpg

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Document 30 - file: tm2226999d4_ex5-1img01.jpg

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