<SEC-DOCUMENT>0001725160-23-000126.txt : 20230531
<SEC-HEADER>0001725160-23-000126.hdr.sgml : 20230531
<ACCEPTANCE-DATETIME>20230531213740
ACCESSION NUMBER:		0001725160-23-000126
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20230531
DATE AS OF CHANGE:		20230531

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Zentalis Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001725160
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				823607803
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-39263
		FILM NUMBER:		23982859

	BUSINESS ADDRESS:	
		STREET 1:		1359 BROADWAY, SUITE 801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018
		BUSINESS PHONE:		(212) 433-3791

	MAIL ADDRESS:	
		STREET 1:		1359 BROADWAY, SUITE 801
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10018

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Zentalis Pharmaceuticals, LLC
		DATE OF NAME CHANGE:	20200107

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Zeno Pharma, LLC
		DATE OF NAME CHANGE:	20171212

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Gallagher Cam
		CENTRAL INDEX KEY:			0001557832

	FILING VALUES:
		FORM TYPE:		144

	MAIL ADDRESS:	
		STREET 1:		6042 CORNERSTONE CT. WEST
		STREET 2:		SUITE B
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
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  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001557832</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



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  <formData>
    <issuerInfo>
      <issuerCik>0001725160</issuerCik>
      <issuerName>Zentalis Pharmaceuticals, Inc.</issuerName>
      <secFileNumber>001-39263</secFileNumber>
      <issuerAddress>
        <com:street1>1359 BROADWAY, SUITE 801</com:street1>
        <com:city>New York</com:city>
        <com:stateOrCountry>NY</com:stateOrCountry>
        <com:zipCode>10018</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>212-433-3791</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Cam Gallagher</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Director</relationshipToIssuer>
        <relationshipToIssuer>Officer - President</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Smith Barney LLC</name>
        <address>
          <com:street1>1 New York Plaza, 38th Floor</com:street1>
          <com:city>New York</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10004</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>9242</noOfUnitsSold>
      <aggregateMarketValue>243978.63</aggregateMarketValue>
      <noOfUnitsOutstanding>59485016</noOfUnitsOutstanding>
      <approxSaleDate>05/31/2023</approxSaleDate>
      <securitiesExchangeName>NASDAQ</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common</securitiesClassTitle>
      <acquiredDate>05/30/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Restricted Stock Unit Release</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>9242</amountOfSecuritiesAcquired>
      <paymentDate>05/30/2023</paymentDate>
      <natureOfPayment>NA</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.</remarks>
    <noticeSignature>
      <noticeDate>05/31/2023</noticeDate>
      <planAdoptionDates>
        <planAdoptionDate>08/18/2021</planAdoptionDate>
      </planAdoptionDates>
      <signature>/s/ Melissa Epperly, attorney-in-fact for Cam S. Gallagher</signature>
    </noticeSignature>
  </formData>
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