<SEC-DOCUMENT>0000929638-25-003884.txt : 20251010
<SEC-HEADER>0000929638-25-003884.hdr.sgml : 20251010
<ACCEPTANCE-DATETIME>20251010160623
ACCESSION NUMBER:		0000929638-25-003884
CONFORMED SUBMISSION TYPE:	SCHEDULE 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251010
DATE AS OF CHANGE:		20251010

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Biomea Fusion, Inc.
		CENTRAL INDEX KEY:			0001840439
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-92506
		FILM NUMBER:		251388164

	BUSINESS ADDRESS:	
		STREET 1:		1599 INDUSTRIAL ROAD
		CITY:			SAN CARLOS
		STATE:			CA
		ZIP:			94070
		BUSINESS PHONE:		(650) 980-9099

	MAIL ADDRESS:	
		STREET 1:		1599 INDUSTRIAL ROAD
		CITY:			SAN CARLOS
		STATE:			CA
		ZIP:			94070

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cormorant Asset Management, LP
		CENTRAL INDEX KEY:			0001583977
		ORGANIZATION NAME:           	
		EIN:				462108927
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		857-702-0388

	MAIL ADDRESS:	
		STREET 1:		200 CLARENDON STREET
		STREET 2:		52ND FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cormorant Asset Management, LLC
		DATE OF NAME CHANGE:	20130807
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13D" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13D/A</submissionType>
<previousAccessionNumber>0000929638-23-001060</previousAccessionNumber>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001583977</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>



</filerInfo>
</headerData>
<formData>
<coverPageHeader>
<amendmentNo>3</amendmentNo>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<dateOfEvent>10/08/2025</dateOfEvent>
<previouslyFiledFlag>false</previouslyFiledFlag>
<issuerInfo>
<issuerCIK>0001840439</issuerCIK>
<issuerCUSIP>09077A106</issuerCUSIP>
<issuerName>Biomea Fusion, Inc.</issuerName>
<address>
<com:street1>1599 INDUSTRIAL ROAD</com:street1>
<com:city>SAN CARLOS</com:city>
<com:stateOrCountry>CA</com:stateOrCountry>
<com:zipCode>94070</com:zipCode>
</address>
</issuerInfo>
<authorizedPersons>
<notificationInfo>
<personName>Neb Obradovic</personName>
<personPhoneNum>857-702-0386</personPhoneNum>
<personAddress>
<com:street1>Cormorant Asset Management, L.P.</com:street1>
<com:street2>200 Clarendon Street, 52nd Floor</com:street2>
<com:city>Boston</com:city>
<com:stateOrCountry>MA</com:stateOrCountry>
<com:zipCode>02116</com:zipCode>
</personAddress>
</notificationInfo>
</authorizedPersons>
</coverPageHeader>
<reportingPersons>
<reportingPersonInfo>
<reportingPersonCIK>0001618442</reportingPersonCIK>
<reportingPersonName>Cormorant Global Healthcare Master Fund, LP</reportingPersonName>
<memberOfGroup>b</memberOfGroup>
<fundType>WC</fundType>
<citizenshipOrOrganization>E9</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>1795928</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>1795928</sharedDispositivePower>
<aggregateAmountOwned>1795928</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>2.59</percentOfClass>
<typeOfReportingPerson>PN</typeOfReportingPerson>
</reportingPersonInfo>
<reportingPersonInfo>
<reportingPersonCIK>0001618451</reportingPersonCIK>
<reportingPersonName>Cormorant Global Healthcare GP, LLC</reportingPersonName>
<memberOfGroup>b</memberOfGroup>
<fundType>AF</fundType>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>1795928</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>1795928</sharedDispositivePower>
<aggregateAmountOwned>1795928</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>2.59</percentOfClass>
<typeOfReportingPerson>OO</typeOfReportingPerson>
</reportingPersonInfo>
<reportingPersonInfo>
<reportingPersonCIK>0001817320</reportingPersonCIK>
<reportingPersonName>Cormorant Private Healthcare Fund III LP</reportingPersonName>
<memberOfGroup>b</memberOfGroup>
<fundType>WC</fundType>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>1717232</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>1717232</sharedDispositivePower>
<aggregateAmountOwned>1717232</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>2.48</percentOfClass>
<typeOfReportingPerson>PN</typeOfReportingPerson>
</reportingPersonInfo>
<reportingPersonInfo>
<reportingPersonNoCIK>Y</reportingPersonNoCIK>
<reportingPersonName>Cormorant Private Healthcare GP III, LLC</reportingPersonName>
<memberOfGroup>b</memberOfGroup>
<fundType>AF</fundType>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>1717232</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>1717232</sharedDispositivePower>
<aggregateAmountOwned>1717232</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>2.48</percentOfClass>
<typeOfReportingPerson>OO</typeOfReportingPerson>
</reportingPersonInfo>
<reportingPersonInfo>
<reportingPersonCIK>0001583977</reportingPersonCIK>
<reportingPersonName>Cormorant Asset Management, LP</reportingPersonName>
<memberOfGroup>b</memberOfGroup>
<fundType>AF</fundType>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>3570872</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>3570872</sharedDispositivePower>
<aggregateAmountOwned>3570872</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>5.15</percentOfClass>
<typeOfReportingPerson>PN</typeOfReportingPerson>
</reportingPersonInfo>
<reportingPersonInfo>
<reportingPersonCIK>0001599214</reportingPersonCIK>
<reportingPersonName>Chen Bihua</reportingPersonName>
<memberOfGroup>b</memberOfGroup>
<fundType>AF</fundType>
<citizenshipOrOrganization>X1</citizenshipOrOrganization>
<soleVotingPower>110792</soleVotingPower>
<sharedVotingPower>3570872</sharedVotingPower>
<soleDispositivePower>110792</soleDispositivePower>
<sharedDispositivePower>3570872</sharedDispositivePower>
<aggregateAmountOwned>3681664</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>5.31</percentOfClass>
<typeOfReportingPerson>IN</typeOfReportingPerson>
</reportingPersonInfo>
</reportingPersons>
<items1To7>
<item1>
<securityTitle>Common Stock</securityTitle>
<issuerName>Biomea Fusion, Inc.</issuerName>
<issuerPrincipalAddress>
<com:street1>1599 INDUSTRIAL ROAD</com:street1>
<com:city>SAN CARLOS</com:city>
<com:stateOrCountry>CA</com:stateOrCountry>
<com:zipCode>94070</com:zipCode>
</issuerPrincipalAddress>
<commentText>This Amendment No. 3 to Schedule 13D (this "Amendment") relates to Common Stock of Biomea Fusion, Inc., a Delaware corporation (the "Issuer" or the "Company").  The address of the principal executive offices of the Issuer is 1599 Industrial Road, San Carlos, CA 94070.  This Amendment is being filed by the Reporting Persons to amend the Schedule 13D that was filed on April 30, 2021, as amended by Amendment No. 1 filed on April 3, 2023, and Amendment No. 2 filed on July 22, 2025 (as so amended, the "Schedule 13D").  Unless otherwise indicated, all capitalized terms used herein but not defined herein shall have the same meaning as in the Schedule 13D.</commentText>
</item1>
<item2>
<filingPersonName>Cormorant Global Healthcare Master Fund, LP&#13;
Cormorant Global Healthcare GP, LLC&#13;
Cormorant Private Healthcare Fund III, LP&#13;
Cormorant Private Healthcare GP III, LLC&#13;
Cormorant Asset Management, LP&#13;
Bihua Chen</filingPersonName>
<principalBusinessAddress>200 Clarendon Street, 52nd Floor&#13;
Boston, MA 02116</principalBusinessAddress>
<citizenship>Cormorant Global Healthcare Master Fund, LP - Cayman Islands&#13;
Cormorant Global Healthcare GP, LLC - Delaware&#13;
Cormorant Private Healthcare Fund III, LP - Delaware&#13;
Cormorant Private Healthcare GP III, LLC - Delaware&#13;
Cormorant Asset Management, LP - Delaware&#13;
Bihua Chen - United States</citizenship>
</item2>
<item5>
<percentageOfClassSecurities>See Items 7-13 of the cover page and Item 2.</percentageOfClassSecurities>
<numberOfShares>See Items 7-13 of the cover page and Item 2.&#13;
&#13;
The percentages reported herein with respect to the Reporting Persons' holdings are calculated based upon (i) a statement in a Prospectus filed by the Issuer on October 7, 2025 that there would be 69,322,377 shares of Common Stock outstanding following the closing of a public offering described therein, and (ii) a statement in a Current Report on Form 8-K filed by the Issuer on October 7, 2025 reporting that the public offering was expected to close on October 8, 2025. &#13;
&#13;
The shares reported for Bihua Chen reflect shares of Common Stock that she has the right to receive within 60 days upon the exercise of stock options granted to her in her capacity as a director of the Issuer.</numberOfShares>
<transactionDesc>The Reporting Persons did not engage in any transactions in securities of the Issuer during the sixty day period prior to the filing of this Schedule 13D.</transactionDesc>
<listOfShareholders>Not applicable.</listOfShareholders>
<date5PercentOwnership>Not applicable.</date5PercentOwnership>
</item5>
</items1To7>
<signatureInfo>
<signaturePerson>
<signatureReportingPerson>Cormorant Global Healthcare Master Fund, LP</signatureReportingPerson>
<signatureDetails>
<signature>/s/ CORMORANT GLOBAL HEALTHCARE MASTER FUND, LP By: Cormorant Global Healthcare GP, LLC, its General Partner</signature>
<title>By: Bihua Chen, Managing Member</title>
<date>10/10/2025</date>
</signatureDetails>
</signaturePerson>
<signaturePerson>
<signatureReportingPerson>Cormorant Global Healthcare GP, LLC</signatureReportingPerson>
<signatureDetails>
<signature>/s/ Bihua Chen</signature>
<title>By: Bihua Chen, Managing Member</title>
<date>10/10/2025</date>
</signatureDetails>
</signaturePerson>
<signaturePerson>
<signatureReportingPerson>Cormorant Private Healthcare Fund III LP</signatureReportingPerson>
<signatureDetails>
<signature>/s/ CORMORANT PRIVATE HEALTHCARE FUND III, LP By: Cormorant Private Healthcare GP III, LLC, its General Partner</signature>
<title>By: Bihua Chen, Managing Member</title>
<date>10/10/2025</date>
</signatureDetails>
</signaturePerson>
<signaturePerson>
<signatureReportingPerson>Cormorant Private Healthcare GP III, LLC</signatureReportingPerson>
<signatureDetails>
<signature>/s/ Bihua Chen</signature>
<title>By: Bihua Chen, Managing Member</title>
<date>10/10/2025</date>
</signatureDetails>
</signaturePerson>
<signaturePerson>
<signatureReportingPerson>Cormorant Asset Management, LP</signatureReportingPerson>
<signatureDetails>
<signature>/s/ CORMORANT ASSET MANAGEMENT, LP By: Cormorant Asset Management GP, LLC, its General Partner</signature>
<title>By: Bihua Chen, Managing Member</title>
<date>10/10/2025</date>
</signatureDetails>
</signaturePerson>
<signaturePerson>
<signatureReportingPerson>Chen Bihua</signatureReportingPerson>
<signatureDetails>
<signature>/s/ Bihua Chen</signature>
<title>Bihua Chen</title>
<date>10/10/2025</date>
</signatureDetails>
</signaturePerson>
</signatureInfo>
</formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
